Document Detail

Leptomeningeal carcinomatosis associated with oesophageal adenocarcinoma: two case reports and review of the literature.
MedLine Citation:
PMID:  17343079     Owner:  NLM     Status:  MEDLINE    
Leptomeningeal carcinomatosis (LC) is a rare complication of solid tumours. We report two cases of leptomeningeal carcinomatosis in patients with oesophageal adenocarcinoma. Diagnosis of LC can be overlooked without a high index of suspicion. Multifocality of symptoms and signs is the hallmark of LC. The combination of cerebrospinal fluid cytology and magnetic resonance imaging has a high diagnostic accuracy. The prognosis remains poor and therefore all therapies are still palliative.
Karel Goddeeris; Chris Verslype; Guido Wilms; Eric Van Cutsem
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta gastro-enterologica Belgica     Volume:  69     ISSN:  0001-5644     ISO Abbreviation:  Acta Gastroenterol. Belg.     Publication Date:    2006 Oct-Dec
Date Detail:
Created Date:  2007-03-08     Completed Date:  2007-05-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0414075     Medline TA:  Acta Gastroenterol Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  377-80     Citation Subset:  IM    
Department of Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
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MeSH Terms
Adenocarcinoma / diagnosis,  secondary*
Esophageal Neoplasms / pathology*
Magnetic Resonance Imaging
Meningeal Neoplasms / diagnosis,  secondary*
Meninges / pathology,  radiography
Middle Aged

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