| Leptin-like immunoreactivity in the muscle of juvenile sea bass (Dicentrarchus labrax). | |
| | |
MedLine Citation:
|
PMID: 20146346 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The mammalian hormone, leptin, is mainly synthesized in adipose tissue along with other tissues. Leptin plays a role in numerous processes such as in the control of food intake, homeostasis, immune function and reproduction. In this study, we detected and localized leptin immunoreactivity to the muscle of early juvenile sea bass (Dicentrarchus labrax) by Western blot analysis and immunohistochemistry. A leptin immunopositive band with a molecular weight of approximately 16 kDa, corresponding to mammalian leptin, was identified in trunk skeletal muscle homogenate. Furthermore, leptin immunopositive cells were detected in the endomysium of skeletal muscular fibers. These cells showed immunostained cytoplasmic granules and roundish and oval nuclei. The most intense immunostaining was observed in the endomysial space among the superficial red muscular fibers of the trunk. These findings suggest that in early juvenile sea bass, leptin is mostly produced by skeletal muscles. Therefore, during the developmental stage lacking adipose tissue, skeletal muscles can be considered an important source of leptin. As already suggested in mammals, we can hypothesize the potential roles of leptin not only in energy expenditure for muscle contraction but also during muscle differentiation and growth. |
| | |
Authors:
|
Chiara Gambardella; Sara Ferrando; Lorenzo Gallus; Silvia Ravera; Paolo Bianchini; Paola Ramoino; Salvatore Fasulo; Grazia Tagliafierro |
Related Documents
:
|
9016246 - Mr imaging of skeletal muscle metastases. 22208856 - Extraforaminal ligaments of the cervical spinal nerves in humans. 11343836 - In vivo protection of a water-soluble derivative of vitamin e, trolox, against methylme... 21153546 - The relationship of neural structures to arthroscopic posterior portals according to kn... 9628506 - Objective measures of laryngeal function after reinnervation of the anterior and poster... 14704796 - Glut11, but not glut8 or glut12, is expressed in human skeletal muscle in a fibre type-... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Microscopy research and technique Volume: 73 ISSN: 1097-0029 ISO Abbreviation: Microsc. Res. Tech. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-23 Completed Date: 2010-11-10 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9203012 Medline TA: Microsc Res Tech Country: United States |
Other Details:
|
Languages: eng Pagination: 797-802 Citation Subset: IM |
Copyright Information:
|
(c) 2010 Wiley-Liss, Inc. |
Affiliation:
|
Department of Animal Biology and Marine Ecology, University of Messina, Messina 98166, Italy. chiara.gambardella@unige.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bass* Blotting, Western Immunohistochemistry Leptin / metabolism* Muscle, Skeletal / chemistry*, growth & development |
| Chemical | |
Reg. No./Substance:
|
0/Leptin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Proximal protection in recanalization of totally occluded saphenous vein grafts in acute coronary sy...
Next Document: Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imagi...