| Leptin and IGF-I levels in unconditioned male volunteers after short-term exercise. | |
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MedLine Citation:
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PMID: 10818280 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have previously shown that serum gonadotropins, particularly LH, decline after acute exercise in male volunteers. The mechanism for this decline is unknown. Plasma leptin and IGF-I concentrations were measured in seven male volunteers after acute exercise to exhaustion using the Bruce protocol. Leptin concentrations declined following exercise reaching nadir values 30-120 min after exercise. As anticipated, plasma IGF-I concentrations showed a transient rise immediately after exercise falling thereafter to nadir levels 60-90 min after exercise before returning towards baseline levels. In view of the previously described decline in gonadotropin release after acute exercise, the decline in plasma leptin levels, perhaps related to the rise in IGF-I, may play a role in exercise-induced inhibition of gonadotropin release presumably by inhibition of GnRH secretion. |
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Authors:
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A N Elias; M R Pandian; L Wang; E Suarez; N James; A F Wilson |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Psychoneuroendocrinology Volume: 25 ISSN: 0306-4530 ISO Abbreviation: Psychoneuroendocrinology Publication Date: 2000 Jul |
Date Detail:
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Created Date: 2000-08-03 Completed Date: 2000-08-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7612148 Medline TA: Psychoneuroendocrinology Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 453-61 Citation Subset: IM |
Affiliation:
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Department of Medicine, Division of Endocrinology, UC, Irvine, CA 92717, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Exercise / physiology* Humans Insulin-Like Growth Factor I / metabolism* Kinetics Leptin / metabolism* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Leptin; 67763-96-6/Insulin-Like Growth Factor I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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