Document Detail

Leprosy-specific oral lesions: a report of three cases.
MedLine Citation:
PMID:  18667979     Owner:  NLM     Status:  MEDLINE    
Leprosy is a chronic infection caused by Mycobacterium leprae, a bacillus that presents a peculiar tropism for the skin and peripheral nerves. The clinical spectrum of leprosy ranges from the tuberculoid form (TT) to the disseminative and progressive lepromatous form (LL). Oral lesions are rare but, when present, occur in the lepromatous form. This article describes the clinical and microscopic findings of three cases of LL with oral manifestations. All patients had the lepromatous form and their leprosy-specific oral lesions occurred in the palate. The diagnosis was based on clinical, serological and histopathological findings, and multidrug therapy for multibacillary leprosy was started and continued for 24 months. All patients completed treatment, but developed reaction episodes which were treated with prednisone and/or thalidomide. The authors emphasize the importance of oral mucosa evaluation by a dental health professional during patient care since oral lesions may act as a source of infection.
Ana Carolina F Motta; Marilena C Komesu; Claudia Helena Lovato Silva; Darlene Arruda; João Carlos Lopes Simão; Erika Muller Ramalho Zenha; Renata Bazan Furini; Norma T Foss
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-08-01
Journal Detail:
Title:  Medicina oral, patología oral y cirugía bucal     Volume:  13     ISSN:  1698-6946     ISO Abbreviation:  Med Oral Patol Oral Cir Bucal     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-31     Completed Date:  2008-10-28     Revised Date:  2009-12-11    
Medline Journal Info:
Nlm Unique ID:  101231694     Medline TA:  Med Oral Patol Oral Cir Bucal     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  E479-82     Citation Subset:  D; IM    
Department of Morphology, Stomatology and Physiology, Dental School of Ribeirão Preto, Brazil.
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MeSH Terms
Leprosy, Lepromatous* / diagnosis,  drug therapy
Middle Aged
Mouth Diseases / diagnosis,  drug therapy,  microbiology*
Palate, Soft*

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