Document Detail


Lentigo maligna of the eyelid a rare finding in African Americans.
MedLine Citation:
PMID:  17475333     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To report the case of a 48-year-old African American man with lentigo maligna of the left lower eyelid. DESIGN: Interventional case report. PARTICIPANTS: One patient with lentigo maligna of the left lower eyelid. METHODS: We report the clinical presentation, histopathologic and immunohistochemical features, and treatment of an African American man with lentigo maligna of the eyelid. The current literature regarding this uncommon neoplasm in African American patients also is reviewed. MAIN OUTCOME MEASURES: Histopathologic and immunohistochemical diagnosis and clinical evaluation for recurrence. RESULTS: An excisional biopsy revealed lentigo maligna. An extensive literature search revealed no definitive reports of lentigo maligna or lentigo maligna melanoma of the eyelid in an African American patient. CONCLUSIONS: Although extremely rare, lentigo maligna may involve ocular adnexal skin in African Americans. Awareness and recognition of this premalignant lesion will aid in early diagnosis and treatment and eventually may improve prognosis.
Authors:
Tatyana Milman; W Clark Lambert; Neena Mirani; Paul D Langer
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2007-05-01
Journal Detail:
Title:  Ophthalmology     Volume:  114     ISSN:  1549-4713     ISO Abbreviation:  Ophthalmology     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-06     Completed Date:  2007-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1409-12     Citation Subset:  IM    
Affiliation:
Department of Pathology, University Hospital, New Jersey Medical School, Newark, New Jersey 07101, USA.
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MeSH Terms
Descriptor/Qualifier:
African Americans*
Eyelid Neoplasms / ethnology*,  pathology*
Humans
Hutchinson's Melanotic Freckle / ethnology*,  pathology*
Immunohistochemistry
Male
Melanocytes / pathology
Middle Aged
Skin Neoplasms / ethnology*,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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