Document Detail

Lens opacity increase in a longitudinal study: comparison of the lens opacities classification system II and lensmeter 701.
MedLine Citation:
PMID:  8654109     Owner:  NLM     Status:  MEDLINE    
We evaluated the ability of Lensmeter 701 (LOM) to detect changes in the transparency of the lens graded with the Lens Opacities Classification System II (LOCS II). In this prospective study 410 middle-aged Eastern Finnish men participating in the Kuopio Atherosclerosis Prevention Study were examined three times at eighteen month intervals, and lens opacities were graded with both LOM and LOCS II, the latter serving as the standard. Majority of the change in the LOM reading during the follow-up fell within the 95% tolerance interval of the apparatus (3.08 units). Only four eyes showing progression by LOCS II were detected by LOM. The association between LOM change and the change observed by LOCS II was not statistically significant, and the correspondence of the two methods was weak. It seems that the sensitivity of the LOM is not sufficient to detect small changes in the transparency of the lens over time.
P Rouhiainen; H Rouhiainen; J T Salonen
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Current eye research     Volume:  15     ISSN:  0271-3683     ISO Abbreviation:  Curr. Eye Res.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-07-26     Completed Date:  1996-07-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8104312     Medline TA:  Curr Eye Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  293-7     Citation Subset:  IM    
Research Institute of Public Health, University of Kuopio, Finland.
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MeSH Terms
Anticholesteremic Agents / therapeutic use
Arteriosclerosis / prevention & control
Cataract / classification*,  physiopathology*
Evaluation Studies as Topic
Hypercholesterolemia / complications,  drug therapy
Lens, Crystalline / physiopathology*
Longitudinal Studies
Middle Aged
Ophthalmology / instrumentation*
Pravastatin / therapeutic use
Prospective Studies
Sensitivity and Specificity
Reg. No./Substance:
0/Anticholesteremic Agents; 81093-37-0/Pravastatin

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