| Lemierre syndrome variant: Staphylococcus aureus associated with thrombosis of both the right internal jugular vein and the splenic vein after the exploration of a river cave. | |
| | |
MedLine Citation:
|
PMID: 17221323 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Lemierre syndrome is a rare and potentially fatal entity characterized by septic emboli from thrombosis of the internal jugular vein after oropharyngeal infection. The etiologic agent is not always an anaerobic bacterium. We report a patient with a Lemierre syndrome variant who presented with thrombosis of both the right internal jugular vein and the splenic vein as well as septic pulmonary emboli caused by Staphylococcus aureus, which proved resistant to methicillin, amoxicillin, and ciprofloxacin. The patient was thought to have acquired the infection during the exploration of a river cave in Turkey 10 days before his admission to the hospital. Such caves are natural reservoirs of infectious microorganisms. METHODS: The patient had a physical examination, coagulation screening tests, tests of thrombin generation and fibrinolysis, coagulation inhibitors, activated protein C resistance, early and late serological tests (including autoantibodies), computed tomographic studies of the chest and abdomen, and bacterial examination of peripheral blood. Bacterial investigations were made on samples collected from the river cave. RESULTS: After having undergone a 6 week course of antimicrobial treatment and anticoagulant therapy, the patient recovered from the infection with no residual complications, and the signs and symptoms of Lemierre syndrome resolved. CONCLUSION: The results probably indicate an exposure of the patient to soil-based Staphylococcus aureus. This observation suggests the action of environmental factors that may contribute to the development of this rare syndrome. |
| | |
Authors:
|
Can Boga; Hakan Ozdogu; Banu Diri; Levent Oguzkurt; Suheyl Asma; Mahmut Yeral |
Related Documents
:
|
16543483 - Central venous access devices. 15551293 - Thrombosis associated with l-asparaginase therapy and low fibrinogen levels in adult ac... 2241503 - Ventricular enlargement in schizophrenia evaluated with computed tomographic scanning. ... |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2007-01-13 |
Journal Detail:
|
Title: Journal of thrombosis and thrombolysis Volume: 23 ISSN: 0929-5305 ISO Abbreviation: J. Thromb. Thrombolysis Publication Date: 2007 Apr |
Date Detail:
|
Created Date: 2007-03-14 Completed Date: 2007-04-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9502018 Medline TA: J Thromb Thrombolysis Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 151-4 Citation Subset: IM |
Affiliation:
|
Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Baskent University, 06490 Ankara, Turkey. drcanboga@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Embolism / microbiology Humans Jugular Veins / microbiology, pathology*, ultrasonography Male Pharyngitis / microbiology* Rivers / microbiology Soil Microbiology Splenic Vein / microbiology, pathology*, ultrasonography Staphylococcal Infections / complications* Staphylococcus aureus / pathogenicity Syndrome Thrombosis / microbiology* Tonsillitis / microbiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A dramatic response to rituximab in a patient with resistant thrombotic thrombocytopenic purpura (TT...
Next Document: Heparin resistance in acute coronary syndromes.