Document Detail

Lemierre syndrome in a 5-month-old male infant: Case report and review of the pediatric literature.
MedLine Citation:
PMID:  18779698     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To report, to the best of our knowledge, the youngest patient with Lemierre syndrome. DESIGN: Descriptive case report with review of the pediatric literature. SETTING: Pediatric intensive care unit in a tertiary referral hospital. DATA SOURCE: Systemic review of the literature, including PubMed (English-only journals) and major textbooks. PATIENT: We report a 5-month-old boy who presented with fever and a perforated left-sided otitis media. He developed left-sided complicated otitis media with retroauricular fluid collection, mastoiditis, and temporomandibular joint effusion. The clinical picture was complicated by a left internal jugular vein and left lateral sinus thrombosis. Fusobacterium necrophorum grew in the pus culture. INTERVENTIONS: Low molecular weight heparin. MEASUREMENTS AND MAIN RESULTS: No immunodeficiency and no thrombophilia were identified as predisposing conditions for Lemierre syndrome. Surgical drainage, early and adequate antibiotic treatment, and anticoagulation were followed by complete recovery. CONCLUSIONS: This case report illustrates that Lemierre syndrome can occur in infants without underlying risk factors for severe infections or thrombotic complications.
François Aspesberro; Thomas Siebler; Jean-Paul Van Nieuwenhuyse; Eugène Panosetti; Françoise Berthet
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  9     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-09     Completed Date:  2009-02-26     Revised Date:  2009-04-16    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e35-7     Citation Subset:  IM    
Divisions of Neonatal and Pediatric Intensive Care Unit (FA), Pediatric Radiology (JPVN), Otorhinolaryngology, Head and Neck Surgery (EP), and Pediatrics (FB), Clinique Pédiatrique, Centre Hospitalier de Luxembourg, Luxembourg, USA.
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MeSH Terms
Anticoagulants / therapeutic use
Fever / etiology
Fusobacterium / isolation & purification*
Fusobacterium Infections / complications,  pathology,  radiography*
Heparin, Low-Molecular-Weight / therapeutic use
Jugular Veins / pathology,  radiography
Magnetic Resonance Imaging
Otitis Media / complications*
Sepsis / etiology
Thrombophlebitis / drug therapy,  etiology*
Tomography, X-Ray Computed
Reg. No./Substance:
0/Anticoagulants; 0/Heparin, Low-Molecular-Weight
Comment In:
Pediatr Crit Care Med. 2009 Mar;10(2):276-7; author reply 277   [PMID:  19265373 ]

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