| Leiomyomatosis peritonealis disseminata. An ultrastructural study. | |
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MedLine Citation:
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PMID: 645645 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Electron microscopic features of the eighth documented case of leiomyomatosis peritonealis disseminata identify the main proliferative cell type as a mature leiomyocyte with all its associated ultrastructural features. The histogenesis of this neoplasm is considered to be a multicentric metaplastic change determined by an abnormal tissue response to the elevated hormonal levels occurring in pregnancy or ovarian functioning tumors. It is suggested that the cell of origin is the multipotent subcelomic mesenchymal cell, which retains the capacity to differentiate into several tissues, among them smooth muscle. To illustrate this possibility, myofibroblasts, cells with hybrid characters of fibroblasts and leiomyocytes, were observed; these may represent a transitional stage between the mesenchymal cell and the smooth muscle proliferating cell. |
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Authors:
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F F Nogales; A Matilla; E Carrascal |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of clinical pathology Volume: 69 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 1978 Apr |
Date Detail:
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Created Date: 1978-06-12 Completed Date: 1978-06-12 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 452-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Leiomyoma / ultrastructure* Male Neoplasms, Multiple Primary / ultrastructure* Peritoneal Neoplasms / ultrastructure* Pregnancy Pregnancy Complications / pathology Uterine Neoplasms / ultrastructure* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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