Document Detail


Legumains and their functions in plants.
MedLine Citation:
PMID:  12167328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Legumains are a family of plant and animal Asn-specific cysteine proteinases with extra-cytoplasmic localization in vacuoles or cell walls. Plant legumains are involved in Asn-specific propolypeptide processing during, for example, storage-protein deposition in maturing seeds, when these proteins are resistant against degradation by legumains. With the transition to germination and subsequent seedling growth, storage proteins are opened to unlimited cleavage by legumains, which now contribute to protein mobilization. Here, we suggest a hypothesis that unifies both functions of legumains. Their action as propolypeptide-processing or protein-degrading enzymes is naturally controlled by the conformational state of their substrates, which undergo development- or environment-dependent changes. The suggested substrate conformation-dependent differential roles of legumains might not be restricted to seeds but could also apply to cells of different tissues in vegetative organs.
Authors:
Klaus Müntz; Andrei D Shutov
Related Documents :
9501148 - The chloroplast small heat-shock protein oligomer is not phosphorylated and does not di...
701358 - Membrane proteins synthesized but not processed by isolated maize chloroplasts.
19540618 - Cytokinin-induced changes of nitrogen remobilization and chloroplast ultrastructure in ...
16406368 - Functional expression of the taste-modifying protein, miraculin, in transgenic lettuce.
19833078 - Stability of cry1ab protein during long-term storage for standardization of insect bioa...
3060468 - Yeast actin-binding proteins: evidence for a role in morphogenesis.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Trends in plant science     Volume:  7     ISSN:  1360-1385     ISO Abbreviation:  Trends Plant Sci.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-08-08     Completed Date:  2002-10-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9890299     Medline TA:  Trends Plant Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  340-4     Citation Subset:  IM    
Affiliation:
Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK), Gatersleben, Germany. muentz@IPK-gatersleben.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Cell Wall / enzymology
Cysteine Endopeptidases / biosynthesis,  classification,  genetics,  metabolism*
Evolution
Gene Expression Regulation, Plant
Plants / cytology,  enzymology*,  genetics,  metabolism
Protein Conformation
Protein Processing, Post-Translational*
Protein Transport
Seeds / enzymology
Substrate Specificity
Vacuoles / enzymology
Chemical
Reg. No./Substance:
EC 3.4.22.-/Cysteine Endopeptidases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Recent breakthroughs in the study of salicylic acid biosynthesis.
Next Document:  Transport of carbon in non-green plastids.