Document Detail

Legal issues for chem-bioinformatics models .
MedLine Citation:
PMID:  23276995     Owner:  NLM     Status:  In-Data-Review    
Chem-Bioinformatic models connect the chemical structure of drugs and/or targets (protein, gen, RNA, microorganism, tissue, disease...) with drug biological activity over this target. On the other hand, a systematic judicial framework is needed to provide appropriate and relevant guidance for addressing various computing techniques as applied to scientific research in biosciences frontiers. This article reviews both: the use of the predictions made with models for regulatory purposes and how to protect (in legal terms) the models of molecular systems per se, and the software used to seek them. First we review: i) models as a tool for regulatory purposes, ii) Organizations Involved with Validation of models, iii) Regulatory Guidelines and Documents for models, iv) Models for Human Health and Environmental Endpoint, and v) Difficulties to Validation of models, and other issues. Next, we focused on the legal protection of models and software; including: a short summary of topics, and methods for legal protection of computer software. We close the review with a section that treats the taxes in software use.
Aliuska Duardo-Sanchez; Humberto Gonzalez-Diaz
Related Documents :
17985655 - Evolutionary relationships among prehistoric human populations: an evaluation of relate...
20875065 - Asymmetric dispersal of southern bull-kelp (durvillaea antarctica) adults in coastal ne...
19389735 - A bayesian segmentation approach to ascertain copy number variations at the population ...
19269705 - Use of epidemiologic information in targeted surveillance for population inference.
22415805 - Using phenx measures to identify opportunities for cross-study analysis.
20652935 - Sesamoids in anurans: new data, old issues.
Publication Detail:
Type:  Journal Article     Date:  2013-01-01
Journal Detail:
Title:  Frontiers in bioscience (Elite edition)     Volume:  5     ISSN:  1945-0508     ISO Abbreviation:  Front Biosci (Elite Ed)     Publication Date:  2013  
Date Detail:
Created Date:  2013-01-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485240     Medline TA:  Front Biosci (Elite Ed)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  361-74     Citation Subset:  IM    
Department of Especial Public Law, Faculty of Law, University of Santiago de Compostela (USC), 15782, Santiago de Compostela, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Biomaterial scaffolds for tissue engineering .
Next Document:  Regulatory issues in management of chemicals in OECD member countries .