Document Detail


Leg free fatty acid kinetics during exercise in men and women.
MedLine Citation:
PMID:  10644544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We previously reported that epinephrine stimulates leg free fatty acid (FFA) release in men but not in women. The present studies were conducted to determine whether the same is true during exercise. Six men and six women bicycled for 90 min at 45% of peak O(2) consumption, during which time systemic and leg FFA kinetics ([9, 10-(3)H]palmitate) were measured. The catecholamine and hormonal responses to exercise were not different in men and women. The baseline systemic and leg palmitate release was 94 +/- 15 vs. 114 +/- 5 micromol/min and 16 +/- 2 and 20 +/- 3 micromol/min, respectively, in men and women [P = nonsignificant (NS)]. Systemic and leg palmitate release increased (both P < 0.001) to 251 +/- 18 vs. 212 +/- 16 micromol/min and 73 +/- 19 vs. 80 +/- 12 micromol/min in men and women, respectively, during the last 30 min of exercise (P = NS, men vs. women). We conclude that the systemic and leg adipose tissue lipolytic response to exercise is not different in nonobese men and women.
Authors:
B Burguera; D Proctor; N Dietz; Z Guo; M Joyner; M D Jensen
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of physiology. Endocrinology and metabolism     Volume:  278     ISSN:  0193-1849     ISO Abbreviation:  Am. J. Physiol. Endocrinol. Metab.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-03-06     Completed Date:  2000-03-06     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  100901226     Medline TA:  Am J Physiol Endocrinol Metab     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  E113-7     Citation Subset:  IM    
Affiliation:
Endocrine Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Exercise / physiology*
Fatty Acids, Nonesterified / blood*
Female
Humans
Kinetics
Leg / blood supply*
Male
Palmitates / blood
Grant Support
ID/Acronym/Agency:
DK-45353/DK/NIDDK NIH HHS; DK-50456/DK/NIDDK NIH HHS; RR-00585/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Fatty Acids, Nonesterified; 0/Palmitates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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