Document Detail


Left ventricular trabeculae: quantification in different cardiac diseases and impact on left ventricular morphological and functional parameters assessed with cardiac magnetic resonance.
MedLine Citation:
PMID:  19543106     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Left ventricle trabeculae (LVT) are frequently seen in different cardiac diseases. Normal reference values of LVT in different cardiac conditions are not known. The aim of the study was to quantify with cardiac magnetic resonance (CMR), LVT mass (LVTM) and LVTM percentage (LVTM%) in different heart diseases and to evaluate their influence on left ventricular morphological and functional parameters. METHODS: Fifty-nine patients (14 controls, 17 ischemic cardiomyopathy, 15 nonischemic dilated cardiomyopathy, 7 valvular heart disease and 6 with left ventricle hypertrophy) were enrolled. Cine-MR images were acquired with steady-state free-precession sequence in a short-axis view. LVTM was calculated as the difference between LVM excluding/including trabecuale from the blood cavity. LVTM% was calculated as the percentage of the whole left ventricle mass excluding trabeculae from the blood cavity. RESULTS: Mean age was 47.60 +/- 22.03 years; male 62.7%. Mean LVTM was of 33.38 +/- 16.1 g with mean LVTM% of 19.22 +/- 6.5%. Significant differences between groups for both parameters with P values of 0.02 were obtained. Nonischemic dilated cardiomyopathy showed the highest degree of LVTM (44.73 +/- 16.0 g) and LVTM% (23.26 +/- 6%). Significant differences were noted in left ventricular morphological and functional parameters with inclusion/exclusion of LVT in the myocardial mass. CONCLUSIONS: Reference values and differences of LVTM and LVTM% in various cardiac conditions are given for the first time. Quantification of these parameters with CMR may be clinically useful in the differential diagnosis between left ventricular noncompaction and other cardiac diseases. Exclusion of LVT from myocardium alters left ventricular morphological and functional parameters, which have significant clinical importance.
Authors:
Covadonga Fernández-Golfín; Marta Pachón; Cecilia Corros; Ana Bustos; Beatriz Cabeza; Joaquín Ferreirós; Leopoldo Pérez de Isla; Carlos Macaya; José Zamorano
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of cardiovascular medicine (Hagerstown, Md.)     Volume:  10     ISSN:  1558-2035     ISO Abbreviation:  J Cardiovasc Med (Hagerstown)     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2010-01-15     Completed Date:  2010-03-25     Revised Date:  2010-09-20    
Medline Journal Info:
Nlm Unique ID:  101259752     Medline TA:  J Cardiovasc Med (Hagerstown)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  827-33     Citation Subset:  IM    
Affiliation:
Cardiac Imaging Unit, Cardiovascular Institute, Hospital Clínico San Carlos. Madrid, Spain. covagolfin@yahoo.es
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cardiomyopathies / diagnosis,  physiopathology
Diagnosis, Differential
Female
Heart Diseases / diagnosis*,  physiopathology
Heart Valve Diseases / diagnosis,  physiopathology
Heart Ventricles / pathology*,  physiopathology
Humans
Hypertrophy, Left Ventricular / diagnosis,  physiopathology
Isolated Noncompaction of the Ventricular Myocardium / diagnosis,  physiopathology
Magnetic Resonance Imaging, Cine*
Male
Middle Aged
Predictive Value of Tests
Ventricular Function, Left*
Comments/Corrections
Comment In:
J Cardiovasc Med (Hagerstown). 2010 Jul;11(7):477   [PMID:  20516804 ]
J Cardiovasc Med (Hagerstown). 2010 Jul;11(7):552-3   [PMID:  20035233 ]
J Cardiovasc Med (Hagerstown). 2010 Jul;11(7):552   [PMID:  20527714 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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