Document Detail

Left ventricular thrombosis and cerebrovascular accident in acute myocardial infarction.
MedLine Citation:
PMID:  6721949     Owner:  NLM     Status:  MEDLINE    
In a prospective study of 90 consecutive patients with acute myocardial infarction, 15 (28.3%) of 53 patients with an anterior wall infarction developed a left ventricular thrombosis diagnosed by cross sectional echocardiography. Patients received anticoagulants only after a left ventricular thrombosis had been diagnosed. Twenty eight patients had an inferior infarction, but none of these had a left ventricular thrombosis. Five (5.5%) of the 90 patients suffered a cerebrovascular accident, and all had an anterior wall infarction. In four of these five patients a left ventricular thrombosis was confirmed by echocardiography before the cerebrovascular accident. All patients with left ventricular thrombosis had apical akinesis. The incidence of a thrombosis did not differ in patients with a first anterior myocardial infarction and with reinfarctions. Among the 40 patients with a first anterior wall infarction, 12 with a thrombosis had a significantly higher incidence of enlarged heart on chest radiographs and significantly higher serum aspartate aminotransferase enzyme activity than those without. Thus patients with a large anterior wall infarction and with akinesis in the apical region are at high risk of developing a left ventricular thrombosis, which may be a source of peripheral emboli. Left ventricular thrombosis appears to be rare with infarctions in other locations.
K A Johannessen; J E Nordrehaug; G von der Lippe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  51     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-07-06     Completed Date:  1984-07-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  553-6     Citation Subset:  AIM; IM    
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MeSH Terms
Aspartate Aminotransferases / blood
Cerebrovascular Disorders / etiology*
Coronary Disease / diagnosis,  etiology*
Middle Aged
Myocardial Infarction / complications*,  diagnosis
Prospective Studies
Reg. No./Substance:
EC Aminotransferases

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