Document Detail


Left ventricular structural characteristics in unilateral renovascular hypertension and primary aldosteronism.
MedLine Citation:
PMID:  2973734     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To assess the importance of the renin-angiotensin system and plasma volume as determinants of hypertensive left ventricular hypertrophy and its anatomy, patients with unilateral renovascular hypertension and primary aldosteronism were studied by echocardiography. Blood pressure, age and sex were matched as closely as possible. The 19 patients with unilateral renovascular hypertension and the 19 patients with primary aldosteronism were similar in age, sex and blood pressure (168 +/- 19/97 +/- 11 and 163 +/- 17/99 +/- 10 mm Hg, respectively), but plasma volume was increased in the patients with primary aldosteronism. Interventricular septal thickness, left ventricular posterior wall thickness, left ventricular mass index and relative wall thickness did not differ between the 2 groups of patients. There was a significant correlation between the level of systolic blood pressure and either left ventricular mass index (r = 0.34, p less than 0.05) or relative wall thickness (r = 0.58, p less than 0.001) in both groups of patients. Left ventricular end-diastolic dimension index was increased in the patients with primary aldosteronism compared with those with unilateral renovascular hypertension (3.2 +/- 0.4 vs 2.9 +/- 0.3 cm/m2, p less than 0.02). When confined to the patients with systolic pressure greater than or equal to 150 mm Hg, relative wall thickness was significantly increased in the patients with unilateral renovascular hypertension. Patients with primary aldosteronism and unilateral renovascular hypertension of similar blood pressure levels, age and sex have almost identical degrees of left ventricular hypertrophy and anatomy. In contrast, the patients with primary oldosteronism had increased left ventricular dimension index.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
T Suzuki; H Abe; S Nagata; F Saitoh; S Iwata; A Ashizawa; M Kuramochi; T Omae
Related Documents :
2992564 - Effects of nicardipine on aldosterone release and pressor mechanisms.
9854594 - Essential hypertension: first reason for persistent hypertension after unilateral adren...
3059064 - Clinical applications of antimineralocorticoids.
11513324 - Influence of head-down bed rest on the circadian rhythms of hormones and electrolytes i...
3839174 - Hemodynamic and respiratory effects of dezocine, ciramadol, and morphine.
21666094 - Effectiveness of amlodipine-valsartan single-pill combinations: hierarchical modeling o...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  62     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1988 Dec 
Date Detail:
Created Date:  1989-01-03     Completed Date:  1989-01-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1224-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Hypertension, National Cardiovascular Center, Osaka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aldosterone / blood
Blood Pressure
Blood Volume
Cardiomegaly / pathology*,  physiopathology
Echocardiography
Female
Humans
Hyperaldosteronism / blood,  pathology*,  physiopathology
Hypertension, Renovascular / blood,  pathology*,  physiopathology
Male
Middle Aged
Renin / blood
Chemical
Reg. No./Substance:
52-39-1/Aldosterone; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Transductal balloon angioplasty for coarctation of the aorta in the neonate: preliminary observation...
Next Document:  Identification of best electrocardiographic leads for diagnosing left ventricular hypertrophy by sta...