| Left ventricular pressure/volume relationship in coronary artery disease. | |
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MedLine Citation:
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PMID: 3739885 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined the changes during exercise in LV EF and P/V relationship (systolic blood pressure/end-systolic volume index ratio) in 287 patients. Normal range (mean +/- standard deviation) for exercise EF, exercise P/V, and the changes from rest to exercise (delta) in EF and P/V were established in 51 subjects with less than 1% probability of CAD. The results were compared to those obtained in 53 patients with normal coronary angiograms and 183 patients with angiographically proven CAD. Abnormality in either delta EF or percent delta P/V were observed in 76% of the patients with one-vessel disease and in 91% of patients with multivessel disease. Abnormalities in either delta EF or percent delta P/V were more common than delta EF alone in the total CAD group and in subgroups stratified according to the resting EF, extent of CAD, and adequacy of exercise end points. Similar results were obtained when absolute exercise EF or exercise P/V were used. Abnormalities in the percent delta P/V or delta EF were also seen in 26 of the 53 patients with normal coronary angiograms. Thus, abnormalities in the P/V relationship or EF during exercise are more common than abnormalities in the EF alone. Relative and absolute measurements provide similar results. |
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Authors:
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A S Iskandrian; J Heo |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American heart journal Volume: 112 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1986 Aug |
Date Detail:
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Created Date: 1986-09-17 Completed Date: 1986-09-17 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 375-81 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Coronary Disease / physiopathology*, radionuclide imaging Exercise Test Female Heart / radionuclide imaging Heart Ventricles / physiopathology Humans Male Middle Aged Myocardial Contraction* Physical Exertion Stroke Volume* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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