Document Detail


Left ventricular pressure-volume relations with transesophageal echocardiographic automated border detection: comparison with conductance-catheter technique.
MedLine Citation:
PMID:  8604636     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pressure-volume relations are important means used to assess left ventricular (LV) contractility; however, on-line volume acquisition has been limited to the invasive conductance catheter. The objective was to compare simultaneous measures of LV volume by transesophageal echocardiographic automated border detection (ABD) and conductance catheter and their respective pressure-volume relations during steady state and alterations in preload and contractility. Seven dogs had placement of high-fidelity pressure and conductance catheters, a vena caval balloon occluder, and a transesophageal probe. An automated Simpson's rule volume algorithm was used from the transverse four-chamber view. Inotropic modulation was induced with dobutamine in four dogs and propranolol in three. Relative changes in ABD volume were linearly related to conductance volume at steady state with group mean r = 0.93 +/- 0.03, standard error of estimate (SEE) = 10 +/- 2%. Changes in end-diastolic volume, end-systolic volume, and stroke work with caval occlusion were also significantly correlated:r = 0.93 =/- 0.04, SEE = 3.6 ml; r = 0.89 +/- 0.04, SEE = 3.8 +/- 1.9 ml; and r = 0.86 +/- 0.05, SEE = 40 +/- 21 mJ, respectively. The overall bias was for absolute ABD volume to be less. End-systolic and maximal elastance values by ABD were significantly higher than by the conductance method; baseline group average 4.97 +/- 0.92 mm Hg/ml versus 2.70 +/- 1.15 mm Hg/ml and 6.63 +/- 1.66 mm Hg/ml versus 3.20 +/- 1.37 mm Hg/ml (p<0.05), respectively. However, the direction and relative magnitude of changes in elastance with inotropic modulation were similar.
Authors:
J Gorcsan; A Denault; W A Mandarino; M R Pinsky
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  131     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-05-15     Completed Date:  1996-05-15     Revised Date:  2009-03-17    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  544-52     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiology, University of Pittsburgh Medical Center, Pennsylvania 15213-2582, USA.
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Animals
Dogs
Echocardiography, Transesophageal / instrumentation,  methods*
Electric Conductivity
Evaluation Studies as Topic
Fourier Analysis
Heart Catheterization / instrumentation,  methods*
Myocardial Contraction / physiology
Signal Processing, Computer-Assisted
Stroke Volume / physiology*
Ventricular Pressure / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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