Document Detail


Left ventricular noncompaction cardiomyopathy.
MedLine Citation:
PMID:  24015429     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Isolated Left Ventricular Non Compaction Cardiomyopathy (LVNCC) is a rare genetic cardiomyopathy characterized by a thickened left ventricle with two distinct layers - an inner noncompacted (spongy) layer and an outer compact (dense) layer. The spongy layer is composed of deep intertrabecular recesses. Familial and sporadic forms are known to exist and there is significant genetic heterogeneity among the inherited forms. Symptoms vary and range from asymptomatic to severe heart failure and sudden death. The clinical diagnosis of LVNCC can be challenging partly because there is currently no consensus for diagnostic criteria. As such, many affected individuals are, inopportunely, first diagnosed at post-mortem examination.
Authors:
Kelley Willis Sherling; Theresa Nuttli; William P Newman; Robin R McGoey
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society     Volume:  165     ISSN:  0024-6921     ISO Abbreviation:  J La State Med Soc     Publication Date:    2013 May-Jun
Date Detail:
Created Date:  2013-09-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505618     Medline TA:  J La State Med Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  150-2     Citation Subset:  IM    
Affiliation:
Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, USA.
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