Document Detail

Left ventricular non-noncompaction: The mitral valve prolapse of the 21st century?
MedLine Citation:
PMID:  22658573     Owner:  NLM     Status:  Publisher    
A spongiform epidemic is upon us - myocardial trabeculae are everywhere as left ventricular noncompaction (LVNC) ingratiates itself into modern day cardiology. Current understanding of the condition is evolving but remains incomplete, and brings to mind the chronicles of another great cardiac story: mitral valve prolapse. Anecdote suggests that many individuals with prominent trabeculae may be being falsely labelled with a disease - LVNC - using poor echocardiographic and cardiovascular magnetic resonance criteria. Until we have robust diagnostic criteria, aetiology, clinicopathological significance and prognosis, the risk of casualties from ascertainment bias will remain. We should look to history and learn from past mistakes - specifically from the mitral valve prolapse story to show the way forward for LVNC. Meanwhile, clinicians (and patients) should be wary, bearing in mind the possibility that they might be seeing LVNNC - left ventricular non-noncompaction.
Gabriella Captur; Andrew S Flett; Daniel L Jacoby; James C Moon
Related Documents :
22435343 - Safety of flecainide.
2572253 - Treatment of congestive heart failure--state of the art and future trends.
15912253 - The transsylvian trans-limen insular approach to the crural, ambient and interpeduncula...
Publication Detail:
Type:  EDITORIAL     Date:  2012-5-31
Journal Detail:
Title:  International journal of cardiology     Volume:  -     ISSN:  1874-1754     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-6-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
The Heart Hospital and Institute of Cardiovascular Sciences, UCL, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Benefits of combined aerobic/resistance/inspiratory training in patients with chronic heart failure....
Next Document:  Estimating GFR among participants in the Chronic Renal Insufficiency Cohort (CRIC) Study.