Document Detail

Left ventricular myocardial performance in the fetus with severe tricuspid valve disease and tricuspid insufficiency.
MedLine Citation:
PMID:  15731988     Owner:  NLM     Status:  MEDLINE    
We sought to determine whether left ventricular (LV) function is abnormal in a fetus with severe tricuspid valve disease (TVD), and whether it may contribute to the outcome. We measured the LV Tei index (including isovolumic relaxation [IRT], contraction, and ejection times) in 31 fetuses with TVD, compared the data with measurements from 32 normal fetuses, and correlated these measurements with pulmonary morphology and outcome. LV Tei index was significantly greater, ejection times shorter, and IRT longer in TVD compared with controls. The Tei index was highest in fetuses with either pulmonary insufficiency or atresia compared with those with forward flow. Finally, LV Tei index was significantly greater in fetuses with fetal (n = 5) or neonatal (n = 9) demise than in neonatal survivors (n = 7). Global LV performance as assessed by the Tei index is abnormal in TVD and likely contribute to the high mortality associated with TVD.
Noboru Inamura; Mio Taketazu; Jeffrey F Smallhorn; Lisa K Hornberger
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  22     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-25     Completed Date:  2005-06-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  91-7     Citation Subset:  IM    
Department of Pediatric Cardiology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
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MeSH Terms
Ebstein Anomaly / complications,  physiopathology
Echocardiography, Doppler / methods
Fetal Diseases / physiopathology*,  ultrasonography
Heart Valve Diseases / complications*,  embryology*,  ultrasonography
Pregnancy Outcome
Survival Analysis
Tricuspid Valve / embryology*,  ultrasonography
Tricuspid Valve Insufficiency / complications,  ultrasonography
Ultrasonography, Prenatal / methods
Ventricular Dysfunction, Left / embryology*,  etiology*,  ultrasonography

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