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Left ventricular muscle mass regression after aortic valve replacement.
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MedLine Citation:
PMID:  10576146     Owner:  NLM     Status:  MEDLINE    
Implanting a valve that will reduce left ventricular mass is critical in aortic stenosis. Regression of left ventricular hypertrophy in 46 aortic valve replacement (AVR) patients receiving a St. Jude Medical (SJM) valve was assessed by serial electrocardiographic and echocardiographic studies during the preoperative, immediate, and late postoperative periods. The patients were divided into three groups according to valve size; 19 mm group (n=9), 21 mm group (n=20), and 23+mm group (n=17). There was no surgical mortality. The NYHA functional class improved from an average of 2.2+/-0.8 preoperatively to 1.3+/-0.5 post-operatively. Left ventricular muscle mass index (LVMI) regression failed to reach statistical significance in the 19 mm group, whereas in the other two groups a steady decrease in the LVMI occurred with follow up. ECG findings were less remarkable showing insignificant differences in voltage among the three groups (p=0.000). In conclusion, the current data suggest that the 19 mm SJM valve may not result in satisfactory left ventricular muscle mass regression despite adequate function, even in small patients. Therefore, additional procedures to accommodate a larger valve may be warranted in the aortic annulus smaller than 21 mm.
J W Lee; K J Choi; S G Lee; S J Choo; J O Kim; D H Kang; J K Song; M G Song
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of Korean medical science     Volume:  14     ISSN:  1011-8934     ISO Abbreviation:  J. Korean Med. Sci.     Publication Date:  1999 Oct 
Date Detail:
Created Date:  2000-01-24     Completed Date:  2000-01-24     Revised Date:  2011-03-16    
Medline Journal Info:
Nlm Unique ID:  8703518     Medline TA:  J Korean Med Sci     Country:  KOREA (SOUTH)    
Other Details:
Languages:  eng     Pagination:  511-9     Citation Subset:  IM    
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan, Seoul, Korea.
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MeSH Terms
Aortic Valve / ultrasonography
Aortic Valve Stenosis / complications,  surgery*
Follow-Up Studies
Heart Valve Prosthesis*
Hypertrophy, Left Ventricular / diagnosis,  etiology,  prevention & control*
Middle Aged
Multivariate Analysis
Postoperative Period
Remission Induction
Risk Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Journal Information
Journal ID (nlm-ta): J Korean Med Sci
Journal ID (pmc): jkms
ISSN: 1011-8934
ISSN: 1598-6357
Publisher: Korean Academy of Medical Sciences
Article Information
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Print publication date: Month: 10 Year: 1999
Volume: 14 Issue: 5
First Page: 511 Last Page: 519
ID: 3054451
PubMed Id: 10576146

Left ventricular muscle mass regression after aortic valve replacement.
J. W. Lee Email:
K. J. Choi
S. G. Lee
S. J. Choo
J. O. Kim
D. H. Kang
J. K. Song
M. G. Song
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan, Seoul, Korea.

Article Categories:
  • Research Article

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