Document Detail

Left ventricular morphometric estimation of the coarctation complex in the first year of life.
MedLine Citation:
PMID:  7176077     Owner:  NLM     Status:  MEDLINE    
Coarctation complex is a serious congenital cardiovascular malformation in infants. It is associated with severe congestive cardiac overload and high mortality even after surgical treatment. To investigate left ventricular performance, quantitative morphometry and histometry of the left ventricle were carried out in 19 autopsied patients who died without surgical intervention. The following results were obtained: 1. Coarctation of the aorta was found to selectively affect the left ventricle, showing a volume overload response without effectively adapting to the pressure overload; the right ventricle showed a significant reaction to the pressure overload. 2. The coronary arterioles responded to the pressure load in the left ventricle. In order to promptly recover left ventricular function, simple coarctectomy without VSD closure or other procedures is advisable for treatment of the coarctation complex in the early months of life.
G Shindo; A Mizuno; A Ueno; M Saigusa; M Tsunemoto; R Okada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese heart journal     Volume:  23     ISSN:  0021-4868     ISO Abbreviation:  Jpn Heart J     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1983-02-14     Completed Date:  1983-02-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401175     Medline TA:  Jpn Heart J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  685-96     Citation Subset:  IM    
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MeSH Terms
Aortic Coarctation / complications,  physiopathology*
Cardiac Volume
Ductus Arteriosus, Patent / complications,  physiopathology
Heart / physiopathology*
Heart Septal Defects, Atrial / complications,  physiopathology
Heart Septal Defects, Ventricular / complications,  physiopathology
Heart Ventricles / pathology,  physiopathology
Infant, Newborn
Myocardium / pathology*

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