Document Detail

Left ventricular mass and correlated atherosclerotic risk factors in young adolescents: report from Chin-Shan community cardiovascular study in Taiwan.
MedLine Citation:
PMID:  11254914     Owner:  NLM     Status:  MEDLINE    
Various subclinical disease indicators can be used as an early stage marker of atherosclerosis. Left ventricular (LV) mass has been related to cardiovascular morbidity and mortality. The distribution of LV mass in Chinese is rarely studied and nothing is known about its relationships with various atherosclerotic risk factors in young teenagers, in particular, aspects of lipid profiles. We performed a community-based survey of 523 males and 555 females, aged 12-15, in Chin-Shan, a suburb area near Taipei, Taiwan. LV mass was calculated from the Penn convention. Normalized LV mass by height with power of 2.7 was defined. LV mass and normalized LV mass were significantly greater in males than in females. There were significant positive correlation coefficients between LV mass and age, blood pressure, body mass index, low density lipoprotein cholesterol (LDL-C), apolipoprotein (Apo) B, fasting insulin levels and significant negative correlation coefficients between LV mass and high density lipoprotein cholesterol (HDL-C) and Apo A1 level in both genders. Multiple linear regression models showed gender and body mass index (BMI) were important factors associated with LV mass or normalized values for adolescents. Age and systolic blood pressure were also significant predictors of LV mass, but not of normalized LV mass values. LV mass values were found to be negatively associated with HDL-C values at marginal statistically significant level. Age and BMI are the most significant factors of echocardiographic LV mass distributions in young adolescent in Taiwan. LV mass may also be associated with atherosclerotic risk factors.
K L Chien; F C Sung; H C Hsu; T C Su; Y T Lee
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Atherosclerosis     Volume:  155     ISSN:  0021-9150     ISO Abbreviation:  Atherosclerosis     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-03-20     Completed Date:  2001-06-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  431-7     Citation Subset:  IM    
Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan S. RD, 100, Taipei, Taiwan, ROC.
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MeSH Terms
Apolipoproteins B / blood
Arteriosclerosis / epidemiology*
Blood Pressure
Body Constitution
Body Mass Index
Cholesterol, LDL / blood
Cross-Sectional Studies
Heart Ventricles / anatomy & histology,  ultrasonography
Hypertrophy, Left Ventricular / epidemiology*
Insulin / blood
Lipids / blood
Organ Size
Risk Factors
Suburban Population
Taiwan / epidemiology
Reg. No./Substance:
0/Apolipoproteins B; 0/Cholesterol, LDL; 0/Lipids; 11061-68-0/Insulin

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