| Left ventricular mass as a predictor of development of hypertension. | |
| | |
MedLine Citation:
|
PMID: 1838689 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The mass of left ventricular (LV) muscle plays a central role in hypertension. Echocardiographic LV mass has been shown to reflect the level of blood pressure over time, obesity, diet, and other factors, and to serve as the strongest predictor yet discovered, other than advancing age, of cardiac complications of hypertension. Recent research suggests, in addition, that individuals destined to become hypertensive have increased LV mass before hypertension becomes clinically apparent. Several published studies have compared LV mass in groups of normotensive children to young adults considered to be at high or low genetic risk of hypertension based on the presence or absence of hypertension in their parents. In each instance LV mass was higher in the offspring of hypertensive parents and this difference exceeded that expected for small differences in body habitus or arterial pressure. A longitudinal study in children also showed that LV mass predicted subsequent blood pressure level. We recently performed a study of 132 initially normotensive employed adults, 15 (11%) of whom developed borderline hypertension during a 5-year follow-up. The development of hypertension was not predicted by subject age, body habitus, blood pressure, or a variety of biochemical measurements. The only baseline measurement that predicted development of hypertension was that of LV mass (92 +/- 25 v 77 +/- 19 g/m2, P less than .005), and the likelihood of developing hypertension increased progressively from 3% in the lowest quartile of LV mass of 24% in the highest quartile.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
R B Devereux; G de Simone; M J Koren; M J Roman; J H Laragh |
Related Documents
:
|
12167379 - Diagnosing diastolic heart failure. 19932779 - Left ventricular mass and volume with telmisartan, ramipril, or combination in patients... 2309909 - Influence of adenosine on left ventricular performance in conscious dogs. 7826649 - Bi-ventricular function assessed intraoperatively before and after anatomical correctio... 2869679 - Hemodynamic properties of bucindolol, a beta-adrenoreceptor blocking drug with vasodila... 7782269 - Regional diastolic function in effort angina pectoris: assessment with biplane left ven... 9406159 - Prostaglandins attenuate cardiac contractile dysfunction produced by free radical gener... 15493509 - The effect of heart rate, preload, and afterload on the viscoelastic properties of the ... 6279499 - Chronic potentiation of vasoconstrictor hypertension by adrenocorticotropic hormone. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
|
Title: American journal of hypertension Volume: 4 ISSN: 0895-7061 ISO Abbreviation: Am. J. Hypertens. Publication Date: 1991 Nov |
Date Detail:
|
Created Date: 1992-03-31 Completed Date: 1992-03-31 Revised Date: 2009-02-24 |
Medline Journal Info:
|
Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 603S-607S Citation Subset: IM |
Affiliation:
|
Department of Medicine, New York Hospital-Cornell Medical Center, NY 10021. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cardiomegaly
/
diagnosis* Heart Ventricles / anatomy & histology Humans Hypertension / epidemiology*, pathology* Organ Size Predictive Value of Tests |
| Grant Support | |
ID/Acronym/Agency:
|
HL-18323/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Behavioral, sleep-waking and EEG power spectral effects following the two specific 5-HT uptake inhib...
Next Document: Plasma insulin levels do not change during atrial natriuretic factor infusion in human essential hyp...