Document Detail


Left ventricular involvement in arrhythmogenic right ventricular cardiomyopathy - a scintigraphic and echocardiographic study.
MedLine Citation:
PMID:  15888098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Left ventricular involvement in arrhythmogenic right ventricular cardiomyopathy (ARVC) is a common finding in autopsy studies. In clinical studies using myocardial scintigraphy, MRI and echocardiography, contradictory results have been reported. In this study, we therefore investigated a group of 15 patients with ARVC using thallium-201 (Tl) single-photon emission tomography (SPECT) and echocardiography including assessment of mitral annular motion with M-mode and pulsed tissue Doppler. METHODS: Exercise and rest Tl-201 SPECT were performed in 15 patients with ARVC. The time from diagnosis of the disease varied from less than 1-16 years. All patients fulfilled the established diagnostic criteria for ARVC. An echocardiographic examination, including assessment of left and right ventricular motion and measurements of the mitral annulus motion with M-mode and pulsed tissue Doppler was performed in the patients and in 25 normal subjects. RESULTS: Tl-201 uptake defects in the left ventricular myocardium were present in all except one patient (93%). The uptake defects were predominantly located to the anteroseptal and basal posterior segments. Wall motion abnormalities were seen in the same segments, and in addition to this, in the septal area. In line with this, the total amplitude and the peak systolic velocity of mitral annular motion at the septal point were significantly decreased in the patients compared with the control group. CONCLUSIONS: Our data show that left ventricular involvement is common in ARVC. Tl-201 SPECT and echocardiographic abnormalities were seen not only in patients with long-lasting symptoms but also in asymptomatic patients and in those with short duration of symptoms.
Authors:
Lena Lindström; Eva Nylander; Hans Larsson; Bengt Wranne
Related Documents :
10944018 - Fluorine-18 fdg myocardial positron emission tomographic findings before and after pitu...
15682368 - Gated spect assessment of left ventricular function is sensitive to small patient motio...
2783908 - Quantification of myocardial ischemia and infarction with single photon emission comput...
18974648 - Comparison of the usefulness of brain perfusion spect and mibg myocardial scintigraphy ...
9309758 - Deglutition syncope associated with carotid sinus hypersensitivity.
10565778 - Detection of acute myocardial infarction by 99mtc-labeled d-glucaric acid imaging in pa...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical physiology and functional imaging     Volume:  25     ISSN:  1475-0961     ISO Abbreviation:  Clin Physiol Funct Imaging     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-05-12     Completed Date:  2005-09-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101137604     Medline TA:  Clin Physiol Funct Imaging     Country:  England    
Other Details:
Languages:  eng     Pagination:  171-7     Citation Subset:  IM    
Affiliation:
Department of Clinical Physiology, Faculty of Health Science, Linköping University, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Arrhythmogenic Right Ventricular Dysplasia / complications,  radionuclide imaging*,  ultrasonography*
Echocardiography, Doppler, Pulsed
Female
Humans
Male
Middle Aged
Thallium Radioisotopes / diagnostic use
Tomography, Emission-Computed, Single-Photon
Ventricular Dysfunction, Left / etiology,  radionuclide imaging*,  ultrasonography*
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Parathyroid scintigraphy during hypocalcaemia in primary hyperparathyroidism.
Next Document:  Comparison between maximal early diastolic velocity in long-axis direction obtained by M-mode echoca...