Document Detail


Left ventricular hypertrophy: diagnostics pitfalls.
MedLine Citation:
PMID:  15243850     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Isolated left ventricular hypertrophy, in the absence of hypertension or aortic stenosis, is commonly attributed to hypertrophic cardiomyopathy (HCM). According to the clinical setting, however, other differential diagnoses should be considered. The diagnosis of cardiac amyloidosis may be very challenging especially when the clinician is confronted with various aspects typical of both pathologies. The work-up of this case shows how non-invasive cardiac investigations are sometimes not sufficiently conclusive for distinguishing between the two pathologies, and that only endomyocardial biopsy (EMB) can confirm cardiac involvement secondary to systemic amyloidosis. The prognostic and therapeutic differences between the two diseases, as well as the contextual aspects of the case in point--namely a case of multiorgan failure--serve as an example of how a definitive diagnosis can be attained by means of a multidisciplinary approach in order to reach a definitive treatment plan.
Authors:
Robert Francis Bonvini; Edoardo Camenzind
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Swiss medical weekly     Volume:  134     ISSN:  1424-7860     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-07-09     Completed Date:  2004-10-07     Revised Date:  2011-02-15    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  289-92     Citation Subset:  IM    
Affiliation:
Cardiology Division of University Hospital of Geneva, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Amyloidosis / complications,  diagnosis
Cardiomyopathy, Hypertrophic / diagnosis*
Diagnosis, Differential
Electrocardiography
Female
Humans
Hypertrophy, Left Ventricular / diagnosis*,  etiology
Middle Aged

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