Document Detail

Left ventricular hypertrophy and clinical outcome in CAPD patients.
MedLine Citation:
PMID:  11007379     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the clinical outcome of left ventricular hypertrophy (LVH) (left ventricular wall diastole thickness > or = 1.2 cm) detected by echocardiography in nondiabetic, continuous ambulatory peritoneal dialysis (CAPD) patients without dilated cardiomyopathy. DESIGN: A prospective, descriptive study was conducted between 1 July 1995 and 31 January 1998. Patients were followed up for 24 months. SETTING: Peritoneal dialysis unit in a medical school hospital. PATIENTS AND METHODS: Baseline and yearly echocardiograms were carried out on 66 patients receiving CAPD. Cardiac death was assessed. LVH was correlated with outcome. RESULTS: Of 66 nondiabetic CAPD patients without dilated cardiomyopathy, 20 had a normal echocardiogram (LV wall thickness < 1.2 cm), 21 had mild hypertrophy, and 25 severe hypertrophy (LV wall thickness > 1.4 cm in diastole). In the first two groups, 21% were admitted with congestive heart failure (CHF) after starting dialysis. The 1-year cumulative survival was 85% among those with mild hypertrophy and 91% in the normal group. In the group with severe hypertrophy, 57% were admitted at least once with CHF, and the 1-year cumulative survival was 56%. Eighty-two percent of those who died in the severe group, which accounted for the significantly worse survival (p = 0.003), died from cardiac or cerebrovascular causes, compared with none of those with a normal echocardiogram. CONCLUSIONS: Severe LVH was found in a third of our CAPD patients and was associated with a significantly high cardiovascular morbidity and mortality.
S Silaruks; D Sirivongs; D Chunlertrith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis     Volume:  20     ISSN:  0896-8608     ISO Abbreviation:  Perit Dial Int     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2001-01-03     Completed Date:  2001-03-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8904033     Medline TA:  Perit Dial Int     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  461-6     Citation Subset:  IM    
Divisions of Cardiology and Nephrology, Khon Kaen Medical School, Thailand.
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MeSH Terms
Follow-Up Studies
Hypertrophy, Left Ventricular / complications*
Kidney Failure, Chronic / complications*,  therapy*
Middle Aged
Peritoneal Dialysis, Continuous Ambulatory*
Prospective Studies
Treatment Outcome

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