| Left ventricular hypertrophy causes different changes in longitudinal, radial, and circumferential mechanics in patients with hypertension: a two-dimensional speckle tracking study. | |
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MedLine Citation:
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PMID: 21145703 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Systolic reserve is an important compensatory mechanism against increasing afterload. Although longitudinal systolic dysfunction with preserved ejection fraction has been reported in hypertensive hearts, radial and circumferential function has not been fully examined. The aim of this study was to investigate three-directional systolic function and its relationships with left ventricular geometry in asymptomatic hypertensive patients using two-dimensional speckle-tracking imaging. METHODS: Echocardiographic evaluations were performed in 74 hypertensive patients and 55 age-matched control subjects. RESULTS: Longitudinal strain was significantly reduced in the hypertrophy groups compared with that in control subjects (concentric, -15.1 ± 4.0%; eccentric, -15.9 ± 4.4%; control, -18.9 ± 3.3%; P < .05). Conversely, radial strain was significantly higher in the normal geometry group than in control subjects (53.8 ± 19.4% vs 40.3 ± 15.1%, P < .05). However, this augmentation was attenuated in the other geometries. CONCLUSION: Hypertrophic remodeling attenuates compensatory augmentation of radial systolic function and is associated with latent longitudinal systolic dysfunction. |
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Authors:
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Hidemichi Kouzu; Satoshi Yuda; Atsuko Muranaka; Takahiro Doi; Hitomi Yamamoto; Shinya Shimoshige; Mamoru Hase; Akiyoshi Hashimoto; Shigeyuki Saitoh; Kazufumi Tsuchihashi; Tetsuji Miura; Naoki Watanabe; Kazuaki Shimamoto |
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Publication Detail:
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Type: Journal Article Date: 2010-12-10 |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 24 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 192-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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