| Left ventricular geometry and mortality in patients >70 years of age with normal ejection fraction. | |
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MedLine Citation:
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PMID: 17134637 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Numerous studies have indicated that left ventricular (LV) hypertrophy predicts morbidity and mortality, including studies in older patients. The prognostic impact of other LV geometric patterns, including concentric remodeling (CR), compared with LV hypertrophy has not been studied in a large cohort of older patients. Echocardiographic and clinical data were studied in 9,771 consecutive patients aged >70 years with ejection fractions > or =50% who were followed for 3.1 years to determine the impact of LV geometric patterns. CR was the most prevalent pattern (43%), and 16% met criteria for LV hypertrophy. Although patients with CR had significantly lower LV mass indexes than patients with normal structure as well as those with LV hypertrophy, their mortality was 35% higher than that of normal subjects (15.5% vs 11.5%, p <0.0001) and 13% higher than that of patients with eccentric LV hypertrophy (15.5% vs 13.7%, p <0.001) with similar mortality to those with concentric LV hypertrophy (15.5% vs 15.9%). In conclusion, abnormal LV geometry is extremely common in patients aged >70 years with normal systolic function, being present in 59% of this population, with CR (43%) by far the most common LV geometric pattern. Patients aged >70 years with CR have significantly increased mortality compared with similarly aged patients with either normal structure or eccentric LV hypertrophy, with similar increased mortality to those with concentric LV hypertrophy. |
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Authors:
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Carl J Lavie; Richard V Milani; Hector O Ventura; Franz H Messerli |
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Publication Detail:
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Type: Journal Article Date: 2006-10-02 |
Journal Detail:
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Title: The American journal of cardiology Volume: 98 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2006 Nov |
Date Detail:
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Created Date: 2006-11-30 Completed Date: 2007-01-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1396-9 Citation Subset: AIM; IM |
Affiliation:
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Ochsner Medical Center, New Orleans, Louisiana, USA. clavie@ochsner.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Chi-Square Distribution Echocardiography Female Humans Hypertrophy, Left Ventricular / mortality*, physiopathology, ultrasonography Male Prevalence Prognosis Proportional Hazards Models Stroke Volume / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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