Document Detail

Left ventricular geometry and function are related to electrocardiographic characteristics and diagnoses.
MedLine Citation:
PMID:  9784943     Owner:  NLM     Status:  MEDLINE    
We investigated the relationships between echocardiographic indices of left ventricular geometry and function and major electrocardiographic (ECG) abnormalities in 540 elderly (69-74 years old) male participants of a health survey conducted in Uppsala county, Sweden. Comparing men with major ECG abnormalities that were present or absent in various hierarchic mutually exclusive categories, left ventricular mass indexed to body surface area (LVMI) was significantly increased with major Q-waves (P = 0.0002), ST or T-wave abnormalities (P = 0.005), left bundle-branch block (P = 0.005) and also with atrioventricular block type 1 (P = 0.008) and frequent premature beats (P = 0.02). The left atrial diameter was also significantly increased with most ECG abnormalities. The increased LVMI was in left bundle-branch block mainly due to an increased left ventricular diameter, whereas left ventricular wall thickness was increased with frequent premature beats, atrioventricular block type 1 and ST or T-wave abnormalities. The prevalence of Q-waves was highest in eccentric left ventricular hypertrophy, whereas the prevalence of ST or T-wave abnormalities and atrioventricular block type 1 was highest in concentric left ventricular hypertrophy. Both left ventricular systolic (ejection fraction) and diastolic function (E/A) ratio) were inversely related to Sokolow-Lyon QRS amplitude (r = -0.25, P < 0.02 and r = -0.22, P < 0.03 respectively). In conclusion, LVMI was increased in subjects with ECG signs of coronary artery disease as well as in subjects with several other ECG diagnoses. Furthermore, both left ventricular systolic and diastolic dysfunction were related to increased QRS amplitudes. Thus, the finding of ECG abnormalities in elderly men should raise the suspicion of structural and/or functional left ventricular abnormality.
J Sundström; L Lind; B Andrén; H Lithell
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Clinical physiology (Oxford, England)     Volume:  18     ISSN:  0144-5979     ISO Abbreviation:  Clin Physiol     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-12-29     Completed Date:  1998-12-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8309768     Medline TA:  Clin Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  463-70     Citation Subset:  IM    
Department of Public Health, Uppsala University, Sweden.
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MeSH Terms
Atrial Fibrillation / physiopathology
Atrial Flutter / physiopathology
Echocardiography, Doppler
Heart / anatomy & histology*,  physiology*,  physiopathology
Heart Block / physiopathology
Heart Ventricles / anatomy & histology,  physiopathology
Middle Aged
Ventricular Dysfunction, Left / physiopathology*
Ventricular Function
Ventricular Function, Left / physiology*

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