Document Detail


Left ventricular function and the timing of surgical treatment in valvular heart disease.
MedLine Citation:
PMID:  7212509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The problem of when to recommend surgical treatment for valvular heart disease to avoid irreversible left ventricular damage has not been fully resolved. In aortic stenosis, left ventricular function tends to improve after aortic valve replacement even if it is markedly depressed, and operation solely to prevent irreversible left ventricular dysfunction does not seem indicated. In aortic regurgitation, left ventricular function also usually improves postoperatively if moderately depressed, but in an adult with relatively few symptoms operation should be considered when there is progressive or marked cardiomegaly with reduced systolic function. In chronic mitral regurgitation, limited studies indicate that if left ventricular size is markedly increased and the ejection fraction is even mildly reduced, left ventricular function deteriorates postoperatively; in such patients consideration of operation may be warranted even if symptoms are few. It is concluded that operative mortality and morbidity are now sufficiently low that valve replacement or repair can be considered primarily to preserve left ventricular function under certain circumstances.
Authors:
J Ross
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of internal medicine     Volume:  94     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-05-21     Completed Date:  1981-05-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  498-504     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aortic Valve Insufficiency / physiopathology,  surgery
Aortic Valve Stenosis / physiopathology,  surgery
Cardiac Output
Heart Valve Diseases / physiopathology,  surgery*
Heart Ventricles / physiopathology*,  surgery
Humans
Mitral Valve Insufficiency / physiopathology,  surgery
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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