| Left ventricular function studied with MDCT. | |
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MedLine Citation:
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PMID: 16132917 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Accurate determination of left ventricular (LV) myocardial function is fundamental for clinical diagnosis, risk stratification, and estimation of prognosis in patients with ischemic and nonischemic cardiomyopathy. Primarily, multi-detector-row spiral CT (MDCT) of the heart aimed at detecting coronary artery obstruction and cardiac morphology. Multiple studies have demonstrated that retrospectively, ECG-gated MDCT determination of LV volumes and consequently global LV function parameters is feasible in good agreement with established imaging modalities such as cineventriculography, echocardiography, and cine magnetic resonance imaging (CMR). Post-processing tools allow fast and semi-automatic determination of LV function parameters from MDCT data in analogy to known CMR evaluation approaches. Although MDCT is not considered to be first-line modality for LV function assessment, this technique provides accessory dynamic information in patients undergoing MDCT coronary angiography, contributing to combined assessment of cardiac morphology and function without need of additional radiation exposure. MDCT regional LV wall motion analysis at rest is feasible, but further improvement in temporal resolution seems mandatory to match results obtained from competing modalities. This paper will discuss the diagnostic potential of MDCT for assessment of LV function with regards to accuracy and clinical applications, as well as limitations, particularly in comparison with CMR as modality of reference. |
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Authors:
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Kai Uwe Juergens; Roman Fischbach |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2005-08-20 |
Journal Detail:
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Title: European radiology Volume: 16 ISSN: 0938-7994 ISO Abbreviation: Eur Radiol Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-01-20 Completed Date: 2006-07-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 342-57 Citation Subset: IM |
Affiliation:
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Department of Clinical Radiology, University of Muenster, Germany. kujuerg@uni-muenster.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Volume
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physiology Cardiomyopathies / physiopathology, radiography* Coronary Disease / physiopathology, radiography Electrocardiography Feasibility Studies Humans Image Processing, Computer-Assisted* Imaging, Three-Dimensional* Magnetic Resonance Imaging, Cine Myocardial Contraction / physiology Myocardial Ischemia / physiopathology, radiography* Observer Variation Prognosis Sensitivity and Specificity Stroke Volume / physiology Tomography, Spiral Computed* Ventricular Dysfunction, Left / physiopathology, radiography* Ventricular Function, Left / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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