Document Detail


Left ventricular function in adults with atrial septal defect.
MedLine Citation:
PMID:  3112859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixteen patients with secundum atrial defect were catheterized giving emphasis to the analysis of the left ventricle at end systole and mid-ejection. The mean ejection fraction of the group was subnormal 57 + 8% when compared with 30 normal patients (71 + 109) P less than .005. Eight patients showed elevated end-diastolic volumes (156 + 10cc) when compared to our normal group (95% + 10cc) P less than .005. A total of 32 hypokinetic and 35 tardokinetic areas were found. Eight patients were restudied after nitroglycerin (0.4 mg sublingually) with an improvement in the ejection fraction from 54% to 70% (P less than .005) and normalization of most of the hypokinetic areas. No correlation was found between total ejection fraction or total systolic wall motion and the shunt size. Probably these left ventricular wall motion abnormalities are primary and not due to the shunt size.
Authors:
P I Altieri; J Martínez Toro; L Del Valle; M S Torres; H L Banchs; E Guerra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Puerto Rico health sciences journal     Volume:  6     ISSN:  0738-0658     ISO Abbreviation:  P R Health Sci J     Publication Date:  1987 Apr 
Date Detail:
Created Date:  1987-08-28     Completed Date:  1987-08-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8303541     Medline TA:  P R Health Sci J     Country:  PUERTO RICO    
Other Details:
Languages:  eng     Pagination:  17-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Female
Heart Atria / physiopathology
Heart Catheterization
Heart Septal Defects, Atrial / physiopathology*
Humans
Male
Nitroglycerin / pharmacology*
Prospective Studies
Stroke Volume / drug effects*
Chemical
Reg. No./Substance:
55-63-0/Nitroglycerin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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