Document Detail

Left ventricular function and haemodynamics in ponies during exercise and recovery.
MedLine Citation:
PMID:  2920699     Owner:  NLM     Status:  MEDLINE    
Myocardial and haemodynamic responses to strenuous treadmill exercise were monitored with chronically implanted instrumentation in seven physically untrained ponies. In two other ponies, haemodynamics were monitored using a conventional catheter technique. During exercise (mean +/- sem heart rate = 203 +/- 3 beats/min), left ventricular peak systolic ahd end-diastolic blood pressure significantly increased from 125 +/- 2 to 208 +/- 6 mmHg and from 29 +/- 1 to 58 +/- 3 mmHg, respectively (P less than 0.05). Peak positive first derivative of left ventricular pressure (dP/dt) was also increased significantly, (1397 +/- 144 to 6016 +/- 325 mmHg/sec), as were myocardial segment velocity of shortening during systole (dL/dtsys) and stroke work (193 and 109 per cent, respectively). Paradoxically, segment systolic shortening was reduced significantly (P less than 0.05) with respect to resting control values for 10 mins after cessation of exercise, with the maximal reduction of 22 per cent occurring at 2 mins post exercise. In addition, left ventricular segment stroke work decreased significantly to 67 per cent of resting control value at 2 mins post exercise. This study demonstrates that analysis of regional myocardial performance in conjunction with haemodynamic data permits a detailed description of cardiac events during and immediately following exercise, facilitating definition of changes which are not readily reflected by haemodynamics. Based on these findings, the authors conclude that untrained ponies may readily complete short bouts of near-maximal exercise, yet experience significantly diminished left ventricular function in the immediate post exercise period.
K S Rugh; H E Garner; J R Miramonti; D G Hatfield
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Equine veterinary journal     Volume:  21     ISSN:  0425-1644     ISO Abbreviation:  Equine Vet. J.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-04-20     Completed Date:  1989-04-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0173320     Medline TA:  Equine Vet J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  39-44     Citation Subset:  IM    
John M. Dalton Research Center, University of Missouri, Columbia 65211.
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MeSH Terms
Blood Gas Analysis / veterinary
Blood Pressure
Catheters, Indwelling / veterinary
Electrolytes / blood
Heart / physiology*
Heart Rate
Horses / physiology*
Lactates / blood
Physical Exertion*
Stroke Volume
Ventricular Function
Grant Support
Reg. No./Substance:
0/Electrolytes; 0/Lactates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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