Document Detail

Left ventricular function during arm exercise: influence of leg cycling and lower body positive pressure.
MedLine Citation:
PMID:  17138838     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to characterize left ventricular (LV) diastolic filling and systolic performance during graded arm exercise and to examine the effects of lower body positive pressure (LBPP) or concomitant leg exercise as means to enhance LV preload in aerobically trained individuals. Subjects were eight men with a mean age (+/-SE) of 26.8 +/- 1.2 yr. Peak exercise testing was first performed for both legs [maximal oxygen uptake (Vo(2)) = 4.21 +/- 0.19 l/min] and arms (2.56 +/- 0.16 l/min). On a separate occasion, LV filling and ejection parameters were acquired using non-imaging scintography using in vivo red blood cell labeling with technetium 99(m) first during leg exercise performed in succession for 2 min at increasing grades to peak effort. Graded arm exercise (at 30, 60, 80, and 100% peak Vo(2)) was performed during three randomly assigned conditions: control (no intervention), with concurrent leg cycling (at a constant 15% leg maximal Vo(2)) or with 60 mmHg of LBPP using an Anti G suit. Peak leg exercise LV ejection fraction was higher than arm exercise (60.9 +/- 1.7% vs. 55.9 +/- 2.7%; P < 0.05) as was peak LV end-diastolic volume was reported as % of resting value (110.3 +/- 4.4% vs. 97 +/- 3.7%; P < 0.05) and peak filling rate (end-diastolic volume/s; 6.4 +/- 0.28% vs. 5.2 +/- 0.25%). Concomitant use of either low-intensity leg exercise or LBPP during arm exercise failed to significantly increase LV filling or ejection parameters. These observations suggest that perturbations in preload fail to overcome the inherent hemodynamic conditions present during arm exercise that attenuate LV performance.
Jack M Goodman; Michael R Freeman; Leonard S Goodman
Related Documents :
2768718 - Effects of active muscle mass size on cardiopulmonary responses to exercise in congesti...
3959868 - Factors in delayed onset muscular soreness of man.
7607198 - Blood flow velocity in the common carotid artery in humans during graded exercise on a ...
12691438 - Switching curve control of functional electrical stimulation assisted rowing exercise i...
16141378 - Pulse transit time measured from the ecg: an unreliable marker of beat-to-beat blood pr...
20402668 - Selecting exercise regimens and strains to modify obesity and diabetes in rodents: an o...
Publication Detail:
Type:  Journal Article     Date:  2006-11-30
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  102     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-03-07     Completed Date:  2007-04-30     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  904-12     Citation Subset:  IM    
Faculty of Physical Education and Health, University of Toronto, Ontario, Canada M5S 2W6.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arm / physiology*
Exercise / physiology*
Leg / physiology*
Ventricular Function, Left / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Developmental signals do not further accentuate nonuniform postpneumonectomy compensatory lung growt...
Next Document:  Intensity of eccentric exercise, shift of optimum angle, and the magnitude of repeated-bout effect.