| Left ventricular function and coronary artery disease progression early after coronary bypass grafting. | |
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MedLine Citation:
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PMID: 7944716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To investigate the effects of coronary artery disease progression on left ventricular function in patients who suffer angina early after coronary artery bypass grafting, we studied the progression of coronary stenoses, the occurrence of graft occlusions, and measured left ventricular ejection fraction (regional and global) in 34 consecutive patients who underwent repeat angiography 25.2 +/- 3.5 (standard error of the mean) months postoperatively, from a total population of 550 patients who underwent bypass grafting. Resting left ventricular function and stenosis severity were assessed using a computerized, quantitative analysis system. Coronary stenosis progression was defined as an increase in the percentage of the stenotic occlusion by 30% or more, any increase in lesion severity that resulted in total coronary artery occlusion, or the occurrence of a new stenosis that occluded the artery by 50% or more. Group 1 comprised 21 patients with all grafts patent and group 2 comprised 13 patients with one or more grafts occluded (20 of 34 grafts). Coronary artery disease progressed in all patients in group 1, and this involved 22 of 54 (41%) grafted vessels and 3 of 15 (20%) nongrafted vessels (p < 0.05). Coronary artery disease progressed in 11 patients in group 2, involving 15 of 32 (47%) grafted vessels and 1 of 6 (17%) nongrafted vessels (p < 0.01). An increased collateral circulation was observed in both groups. The left ventricular ejection fraction remained unchanged in both groups (group 1, 0.60 +/- 0.03 versus 0.62 +/- 0.03; group 2, 0.62 +/- 0.05 versus 0.62 +/- 0.04 before and after bypass, respectively; p = not significant) and there was no difference between the groups.(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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D Tousoulis; G Davies; T Crake; S K Ohri; P Rao; K M Taylor |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 58 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1994-10-31 Completed Date: 1994-10-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 857-63 Citation Subset: AIM; IM |
Affiliation:
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Cardiothoracic Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London, England. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / diagnosis, physiopathology*, surgery Collateral Circulation Constriction, Pathologic / diagnosis, etiology, physiopathology Coronary Angiography Coronary Artery Bypass* Coronary Vessels / pathology Electrocardiography Exercise Test Female Graft Occlusion, Vascular / diagnosis, etiology, physiopathology* Humans Male Middle Aged Postoperative Complications / diagnosis, etiology, physiopathology* Recurrence Severity of Illness Index Stroke Volume Time Factors Ventricular Function, Left / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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