Document Detail

Left ventricular echogenic focus in the fetal heart: pathologic correlation.
MedLine Citation:
PMID:  7933029     Owner:  NLM     Status:  MEDLINE    
Echogenic foci within the left ventricle of the heart have been found in a minority of fetuses and generally are believed to be a normal variant. The cause and exact location of these foci have remained speculative, however. We identified three fetuses with this sonographic finding in whom pathologic correlation was available. The only consistent histologic finding present in all three fetuses was mineralization within a papillary muscle; the chordae tendineae were normal. One of the three fetuses had trisomy 21. Echogenic foci within the left ventricle of the fetal heart represent papillary muscle mineralization. Until more data are available to investigate any possible association with aneuploidy, an echogenic focus in the left ventricle should still be considered a normal variant.
D L Brown; D J Roberts; W A Miller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  13     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-11-10     Completed Date:  1994-11-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  613-6     Citation Subset:  IM    
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
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MeSH Terms
Calcinosis / pathology,  ultrasonography*
Fetal Diseases / pathology,  ultrasonography*
Fetal Heart / pathology,  ultrasonography*
Heart Ventricles / pathology,  ultrasonography
Papillary Muscles / pathology,  ultrasonography*
Ultrasonography, Prenatal*

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