| Left ventricular diastolic pressure-volume and stress-strain relationship in children. | |
| | |
MedLine Citation:
|
PMID: 4009927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Diastolic pressure and volume (P-V) curves were approximately exponential and fitted the equation, dP/dV = aP + b, where a was left ventricular volume elastic constant. Stress and strain (sigma-epsilon) curves were expressed by the equation, d sigma/d epsilon = k sigma + c, where k was wall stiffness constant. These exponential curves have been fitted over the whole diastole, but theoretically, the mid-diastole should reflect diastolic elastic properties best. In the present study, therefore, special attention was paid to the mid-diastole in each patient, and both P-V and sigma-epsilon relationships were analyzed by fitting the data to the above mentioned curves during this period of time. This analysis was made in two separate groups of patients. One was the control group consisting of 2 patients with normal hearts, 2 patients with mild pulmonary stenosis, and 25 patients with post mucocutaneous lymph node syndrome. The other group consisted of patients with postoperative congenital heart disease, that is, 8 patients with atrial septal defect and 5 patients with tetralogy of Fallot. The elastic constant (a) could not be compared if the size of the hearts differed. The results of the present study, however, demonstrated that the size of the heart was closely related to the constant, a. In the control group, the constant (a) was exponentially related to the size of the heart, and expressed as follows: a = 0.30e-0.037EDV + 0.045 (r = 0.94, p less than 0.01) In contrast, the wall stiffness constant (k) was not related to the size of the heart. After surgical repair of congenital heart disease, the stiffness constant in the left ventricle was normal in patients with postoperative atrial septal defect, while it was significantly increased in patients with postoperative tetralogy of Fallot. |
| | |
Authors:
|
K Yoshii; H Iwao; S Fukuda; Y Mizoguchi; H Sunagawa; S Honda |
Related Documents
:
|
12452307 - Severe mitral regurgitation may prevent mural thrombus formation within the left ventri... 12442927 - Doppler indices of diastolic transmitral flow velocity are invalid indicators of myocar... 14715337 - Use of tissue doppler imaging to facilitate the prediction of events in patients with a... 6226187 - Electrocardiographic changes in the course of antihypertensive treatment. 21238667 - Restorative proctocolectomy with and without protective ileostomy in a pediatric popula... 20962667 - The role of cytology and hpv typing as a screening tool in patients with intraanal warts. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Japanese circulation journal Volume: 49 ISSN: 0047-1828 ISO Abbreviation: Jpn. Circ. J. Publication Date: 1985 Apr |
Date Detail:
|
Created Date: 1985-08-20 Completed Date: 1985-08-20 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 7806868 Medline TA: Jpn Circ J Country: JAPAN |
Other Details:
|
Languages: eng Pagination: 385-94 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cardiac Volume* Child Child, Preschool Diastole* Female Heart Septal Defects, Atrial / physiopathology, surgery Humans Male Mucocutaneous Lymph Node Syndrome / physiopathology Myocardial Contraction* Postoperative Period Pulmonary Valve Stenosis / physiopathology Stress, Physiological / physiopathology* Tetralogy of Fallot / physiopathology, surgery Ventricular Function |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Flushing of spigotted silicone central venous feeding catheters--how often?
Next Document: Effects of nifedipine and diltiazem on hemodynamic responses at rest and during exercise in hyperten...