Document Detail


Left ventricular diastolic dysfunction in chronic aortic dissection.
MedLine Citation:
PMID:  17383339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: In chronic aortic dissection, compression of the true lumen by the expanded false lumen may be a cause of left ventricular afterload elevation, which may result in diastolic dysfunction. We compared the left ventricular diastolic function by echocardiography between those patients who had double-barrel descending aortic dissection and those who did not. METHODS: Twelve patients (mean age, 61 +/- 12 years) with chronic type B aortic dissection were enrolled in this study. Patients in group I had double-barrel aortic dissection that had expanded the patent false lumen and narrowed the true lumen (n = 7, 58.3%), and patients in group II had a wider-caliber true lumen with a thrombosed false lumen (n = 5, 41.7%). We evaluated the left ventricular diastolic function with the transmitral flow pattern (E and A waves) with the pulsed Doppler method and flow propagation velocity (FPV) with color M-mode Doppler images, and classified its severity into grade I (abnormal relaxation), grade II (pseudonormalization) and grade III (restriction). RESULTS: All patients in group II had grade I diastolic dysfunction, with an E/A of less than 1.0. By contrast, 4 of the 7 patients in group I had grade II diastolic dysfunction, with an FPV/E of less than 0.6 and a pseudonormalized (> 1.0) E/A ratio (p = 0.081). Consequently, the E/A ratio was higher in group I than in group II (1.16 +/- 0.39 versus 0.68 +/- 0.18; p < 0.05). CONCLUSIONS: It is suggested that left ventricular diastolic function is severely reduced in the patients having aortic dissection with a double-barrel and narrowed true lumen.
Authors:
Yasushige Shingu; Norihiko Shiiya; Taisei Mikami; Kenji Matsuzaki; Takashi Kunihara; Yoshiro Matsui
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  83     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-26     Completed Date:  2007-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1356-60     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiovascular Surgery, Hokkaido University Hospital, Sapporo, Hokkaido, Japan. fwpc1650@mb.infoweb.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aneurysm, Dissecting / complications*,  surgery,  ultrasonography
Aortic Aneurysm, Thoracic / complications*,  surgery,  ultrasonography
Blood Vessel Prosthesis Implantation / methods
Case-Control Studies
Chronic Disease
Diastole
Echocardiography, Doppler, Color
Female
Follow-Up Studies
Heart Catheterization
Heart Function Tests
Humans
Male
Middle Aged
Probability
Risk Assessment
Severity of Illness Index
Survival Rate
Ventricular Dysfunction, Left / etiology*,  mortality,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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