Document Detail


Left ventricular cavity size determined by preoperative dipyridamole thallium scintigraphy as a predictor of late cardiac events in vascular surgery patients.
MedLine Citation:
PMID:  8615309     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We hypothesized that left ventricular (LV) cavity size measured on dipyridamole thallium scintigraphy identifies patients at risk for late nonfatal myocardial infarction and cardiovascular death. Accordingly, we retrospectively evaluated the predictive value of clinical and scintigraphic variables, including transendocardial LV cavity measurement performed on formatted images, in 335 vascular surgery patients. A nonhomogeneous perfusion pattern and enlarged LV cavity size were the most significant predictors of late events, and the interaction between these two variables was more predictive than was either variable alone. Life-table analysis demonstrated that patients with normal perfusion patterns had the lowest incidence of late events regardless of cavity size (p < 0.0005). Conversely, patients with a nonhomogeneous perfusion pattern and the largest LV cavity measurements were at the highest risk for late cardiac events (p < 0.0001). Therefore, this study demonstrated that a measurement of LV scintigraphic cavity size can provide important risk stratification for late cardiac events.
Authors:
G Emlein; B Villegas; S Dahlberg; J Leppo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  131     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-06-05     Completed Date:  1996-06-05     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  907-14     Citation Subset:  AIM; IM    
Affiliation:
University of Massachusetts Medical Center, Department of Nuclear Medicine, Worcester 01655, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Analysis of Variance
Coronary Disease / mortality,  physiopathology,  radionuclide imaging*
Dipyridamole / diagnostic use*
Heart Ventricles* / radionuclide imaging
Humans
Hypertrophy, Left Ventricular / mortality,  physiopathology*,  radionuclide imaging
Male
Middle Aged
Myocardial Infarction / mortality,  physiopathology,  radionuclide imaging*
Predictive Value of Tests
Preoperative Care
Proportional Hazards Models
Radionuclide Ventriculography*
Thallium Radioisotopes / diagnostic use*
Vascular Surgical Procedures* / mortality
Ventricular Function, Left
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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