Document Detail

Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction.
MedLine Citation:
PMID:  12808278     Owner:  NLM     Status:  MEDLINE    
A 74-year-old woman with hypertension and bronchial asthma had chest discomfort at rest and 4 days later was admitted to her nearby hospital because of the sudden onset of right hemiparesis. The hemiparesis had almost disappeared within 24 h of onset, but because an electrocardiogram showed sinus tachycardia and diffuse symmetrical T-wave inversion, she was referred for cardiac examination. Coronary angiography did not reveal any significant coronary artery stenosis, but left ventriculography revealed severe hypokinesis of the left ventricular apical region, which contained a 4 x 4-mm solid thrombus moving freely with a wavy motion. Moreover, the activity of both protein C and protein S had decreased. The thrombus disappeared after 2 weeks of anticoagulant treatment with warfarin. Her clinical course suggested that the transient cerebral ischemic attack was caused by embolism of the left ventricular thrombus associated with 'tako-tsubo-like left ventricular dysfunction'.
Satoshi Kurisu; Ichiro Inoue; Takuji Kawagoe; Masaharu Ishihara; Yuji Shimatani; Kenji Nishioka; Takashi Umemura; Suji Nakamura; Masashi Yoshida; Hikaru Sato
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  67     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-16     Completed Date:  2004-01-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  556-8     Citation Subset:  IM    
Division of Cardiology, Hiroshima City Hospital, Japan.
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MeSH Terms
Anticoagulants / therapeutic use
Heart Diseases / etiology*
Heart Ventricles / pathology,  radiography
Ischemic Attack, Transient / etiology
Thrombosis / etiology*
Ventricular Dysfunction, Left / classification,  complications*,  physiopathology,  radiography
Warfarin / therapeutic use
Reg. No./Substance:
0/Anticoagulants; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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