Document Detail

Left ventricular aneurysm: pre- and postoperative haemodynamic studies at rest and during exercise.
MedLine Citation:
PMID:  7286025     Owner:  NLM     Status:  MEDLINE    
We studied 9 men with antero-apical left ventricular aneurysms. All suffered from incapacitating angina pectoris without heart failure. Aneurysmectomy was done in 4 patients as the sole procedure while it was combined with revascularisation of the residual myocardium in the other 5. Haemodynamic measurements were made at rest and during submaximal supine-leg exercise before and approximately 6 mth after operation in each patient. Compared to the preoperative levels, we observed a significant increase in respiratory rate at rest (P less than 0.001) and during exercise (P less than 0.01), in ventilation during exercise (P less than 0.05), in mean pulmonary arterial pressure at rest (P less than 0.001) and during exercise (P less than 0.01) and in mean pulmonary wedge pressure during exercise (P less than 0.01). These changes were accompanied by a significant reduction in cardiac output during exercise (P less than 0.01) and in stroke volume at rest (P less than 0.05) and during exercise (P less than 0.01). Heart rate and blood pressure remained essentially unchanged. . The curve representing the relationship between the left ventricular stroke work and the filling pressure shifted downwards and to the right after operation compared to that before operation. Patients who show only minimal haemodynamic disturbances associated with an aneurysm, maintain an effective forward stroke volume by an augmented fibre-shortening of the residual myocardium as well as an increase in the diastolic volume of the heart. Results of our study demonstrated that the compensatory ventricular dilatation may be critical in this group of patients. Despite an increase in average ejection fraction after operation, the removal of the aneurysm led to considerable haemodynamic deterioration in all the patients studied.
P A Majid; R Wardeh; P J De Feyter; J P Roos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardiology     Volume:  12     ISSN:  0301-4711     ISO Abbreviation:  Eur J Cardiol     Publication Date:  1981  
Date Detail:
Created Date:  1981-12-21     Completed Date:  1981-12-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404054     Medline TA:  Eur J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  215-27     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Exercise Test
Heart Aneurysm / physiopathology*,  surgery
Heart Ventricles
Middle Aged
Stroke Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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