Document Detail


Left ventricle-aortic coupling: prediction of contraction pattern.
MedLine Citation:
PMID:  6496699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In control heart beats of six open-chest dogs we established a relationship between ventricular diameter and change in volume during systolic ejection, described ventricular mechanical performance by a time-dependent pressure-diameter relationship, and represented ventricular afterload in subsequent variably loaded test beats by aortic input impedance calculated from aortic flow and pressure. Impedance was manipulated by means of an inflatable balloon in the aorta. A computational procedure was developed which combined the independent and general descriptions of ventricle (1 and 2 above) and load (3 above) to predict the time course and mean values of aortic pressure, flow, ventricular pressure, and diameter over a broad range of aortic impedance. Predicted data were compared with those directly observed at identical impedance. High degree of accordance between predicted and observed data of stroke volume, mean aortic and mean ventricular pressure was found, but diameter shortening was less accurately predicted. Previously assessed dependency of the ventricular pressure-volume-time relationship on aortic flow and "ejection history" was also incorporated in the calculations. This caused improved prediction of the flow pulse configuration, but the quality of predictions of mean values of pressures and flow was not enhanced.
Authors:
H Piene; E S Myhre
Related Documents :
6239049 - Left ventricular function of concentric hypertrophied heart after chronic pressure over...
19808339 - Mechanisms underlying improvements in ejection fraction with carvedilol in heart failure.
7127359 - Left ventricular o2 requirements of pressure and volume loading in the normal canine he...
9321749 - Relation of left ventricular longitudinal and circumferential shortening to ejection fr...
12097979 - A paradigm for quantifying ventricular contraction.
3359589 - Efficiency of energy transfer from pressure-volume area to external mechanical work inc...
11728259 - Cardiorenal protection in diabetes.
9186109 - Postoperative retinal ischemia with self-sealing cataract surgery incisions.
9277539 - Baroreceptor-independent renal nerve inhibition by intracerebroventricular angiotensin ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of physiology     Volume:  247     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-11-30     Completed Date:  1984-11-30     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  H531-40     Citation Subset:  IM; S    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Aorta, Thoracic / physiology*
Blood Pressure
Cardiography, Impedance
Dogs
Heart Function Tests
Myocardial Contraction*
Regression Analysis
Ventricular Function

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Influence of cardiac denervation on subsidiary atrial pacemaker stabilization.
Next Document:  Isotonic length transient of cat heart muscle in Ba2+-induced contracture.