| Left and right ventricular function after streptokinase reperfusion: assessment by gated blood pool scans. | |
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MedLine Citation:
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PMID: 3587794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-three patients with acute anterior or inferior myocardial infarction (AMI, IMI) were investigated by gated blood pool scans at a mean 4.9 h after reperfusion and 10 days later. Eighteen (78%) successful reperfusion cases were divided into two groups; reperfusion in less than 4 h (Rp less than 4 h, n = 9) and reperfusion in more than 4 h (Rp greater than 4 h, n = 9) from the onset of chest pain. As control group, gated blood pool scans were also performed in the early hours following infarction in an additional 42 patients who received conventional treatments. Rp less than 4 h demonstrated significant improvement of mean LVEF in AMI (from 39.5 +/- 3.3 to 50.3 +/- 3.1%, p less than 0.01) and IMI (from 54.6 +/- 4.3 to 60.4 +/- 5.8%, p less than 0.01). Improvement of initially abnormal segments was noticed in 68% of AMI and 65% of IMI by quantitative wall motion analysis, while Rp greater than 4 h showed only slight improvement of LVEF and regional wall motion compared to Rp less than 4 h. On the other hand, the control group showed no significant change in left ventricular performance and regional wall motion. In patients with AMI, RVEF remained within normal range. In IMI, whether reperfused or not, the RVEF showed moderate improvement. In conclusion, these studies indicated that the time of reperfusion and location of infarction may influence functional recovery after streptokinase reperfusion. |
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Authors:
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T Nishimura; T Yasuda; H K Gold; R C Leinbach; K A McKusick; H W Strauss |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 8 ISSN: 0143-3636 ISO Abbreviation: Nucl Med Commun Publication Date: 1987 Feb |
Date Detail:
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Created Date: 1987-07-06 Completed Date: 1987-07-06 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 87-97 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angiography Blood / radionuclide imaging Computers Female Heart / physiopathology* Heart Function Tests Humans Male Middle Aged Movement Myocardial Infarction / drug therapy, radiography, radionuclide imaging Prospective Studies Streptokinase / therapeutic use* Stroke Volume Technetium / diagnostic use Ventricular Function |
| Chemical | |
Reg. No./Substance:
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7440-26-8/Technetium; EC 3.4.-/Streptokinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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