Document Detail

Left ostial stenosis surgical angioplasty.
MedLine Citation:
PMID:  17902063     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Left main coronary stenosis, including ostial lesions, is conventionally treated by coronary bypass surgery. This approach, however, restores a less physiological retrograde perfusion to part of the myocardium and may contribute to a competition of flows in non-occluded coronaries. Direct surgical reconstruction of the LMCA has been described and theoretically avoids these potential drawbacks. METHODS: From May 1995 until December 2005, 25 patients with ostial left main stenosis underwent surgical angioplasty in our unit. Patients were all followed up clinically and with transesophageal echocardiography. RESULTS: Mean age of the patients was 59.7 years (range, 33 - 73 years). The male to female ratio was 14 : 11. The left main coronary stem was approached anteriorly in all patients. The onlay patch consisted of saphenous vein and was extended across the aortotomy suture line. There were no early deaths or perioperative myocardial infarctions. All patients underwent follow-up clinical examination and transesophageal (TOE) echocardiography as well as other investigations when required. TOE demonstrated a wide open left main coronary artery normal flow pattern, and no aneurysmal dilatation or calcification of the onlay patch in 24 patients. After a mean follow-up of 8 years, the all-cause survival was 88 %, while event-free survival was 80 % with 21 pts remaining in CCS I. CONCLUSION: Surgical reconstruction of the LMCA is a safe and effective treatment for left main stenosis. Re-institution of normal blood flow through the left main coronary artery possibly confers advantages over bypass surgery.
K G Perreas; S Dimitriou; E Ntalarizou; P Kalogris; G Amanatidis; M Khoury; G Karatassakis; A Michalis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Thoracic and cardiovascular surgeon     Volume:  55     ISSN:  0171-6425     ISO Abbreviation:  Thorac Cardiovasc Surg     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-09-28     Completed Date:  2008-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903387     Medline TA:  Thorac Cardiovasc Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  424-7     Citation Subset:  IM    
Department of B Cardiac Surgery, Onassis Cardiac Centre, Athens, Greece.
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MeSH Terms
Angioplasty* / adverse effects
Cardiac Surgical Procedures / adverse effects,  methods*
Coronary Angiography
Coronary Circulation
Coronary Stenosis / mortality,  pathology,  physiopathology,  surgery*
Echocardiography, Transesophageal
Follow-Up Studies
Middle Aged
Saphenous Vein / transplantation*
Time Factors
Treatment Outcome
Vascular Patency

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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