Document Detail

Left main percutaneous transluminal coronary angioplasty with the autoperfusion catheter in an animal model.
MedLine Citation:
PMID:  2208267     Owner:  NLM     Status:  MEDLINE    
Left main coronary angioplasty is associated with high risk because of interruption of blood flow to much of the left ventricle during balloon inflation. An "autoperfusion" balloon angioplasty catheter that allows blood to flow passively distal to an inflated balloon was tested in dogs and compared with inflations with standard balloon catheters. During 3 min occlusions of the left main coronary artery with the autoperfusion catheter, regional myocardial blood flow was preserved at 0.60 +/- 0.14 ml/min/g, compared with 0.07 +/- 0.03 ml/min/g during inflation with standard balloon catheters (P less than 0.01). Similarly, at the end of 3 min of inflation, left ventricular systolic pressure and dP/dt were maintained with autoperfusion catheter inflation, but they were severely depressed after standard angioplasty balloon inflation. All seven dogs survived autoperfusion balloon inflation, whereas five of seven developed sustained ventricular tachycardia and/or ventricular fibrillation during or after standard balloon inflation. Thus, distal blood flow, hemodynamics, and survival were preserved during autoperfusion balloon inflation in the left main coronary artery.
Z G Turi; S Rezkella; C A Campbell; R A Kloner
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Catheterization and cardiovascular diagnosis     Volume:  21     ISSN:  0098-6569     ISO Abbreviation:  Cathet Cardiovasc Diagn     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-11-14     Completed Date:  1990-11-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7508512     Medline TA:  Cathet Cardiovasc Diagn     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  45-50     Citation Subset:  IM    
Division of Cardiology, Harper Hospital, Detroit, MI 48201.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary / instrumentation*,  mortality
Coronary Circulation / physiology*
Coronary Disease / prevention & control
Coronary Vessels*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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