Document Detail


Left frontal lobe contributions to concept formation: a quantitative MRI study of performance on the Delis-Kaplan Executive Function System Sorting Test.
MedLine Citation:
PMID:  19031322     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examined relationships between lobar volumes and performance on the Delis-Kaplan Executive Function System (D-KEFS) Sorting Test, a standardized measure of concept formation. There were 89 participants: 19 patients with probable Alzheimer's disease, 25 patients with frontotemporal dementia, 13 patients with semantic dementia, 12 patients with progressive nonfluent aphasia, 9 patients with probable progressive supranuclear palsy, 2 patients with possible progressive supranuclear palsy, and 9 healthy participants. We used BRAINS2 software to generate volumes of the right and left frontal, temporal, and parietal lobes. Multiple regression analysis indicated that, after controlling for Mini-Mental State Examination scores, intracranial volume, and demographic variables, only the left frontal lobe significantly predicted performance on the D-KEFS Sorting Test.
Authors:
Eric M Fine; Dean C Delis; David Dean; Victoria Beckman; Bruce L Miller; Howard J Rosen; Joel H Kramer
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2008-11-24
Journal Detail:
Title:  Journal of clinical and experimental neuropsychology     Volume:  31     ISSN:  1744-411X     ISO Abbreviation:  J Clin Exp Neuropsychol     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-05-21     Completed Date:  2009-08-10     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  8502170     Medline TA:  J Clin Exp Neuropsychol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  624-31     Citation Subset:  IM    
Affiliation:
Psychology Service, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA. efine@ucsd.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Analysis of Variance
Concept Formation / physiology*
Dementia* / classification,  pathology,  physiopathology
Female
Frontal Lobe / pathology,  physiopathology*
Functional Laterality / physiology*
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Models, Biological
Neuropsychological Tests*
Problem Solving / physiology*
Grant Support
ID/Acronym/Agency:
AG019724/AG/NIA NIH HHS; AG02351/AG/NIA NIH HHS; AG12435/AG/NIA NIH HHS; AG22983/AG/NIA NIH HHS; P01 AG019724/AG/NIA NIH HHS; P01 AG019724-07/AG/NIA NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evaluation of antioxidant activity, colour and some nutritional characteristics of pomegranate (Puni...
Next Document:  D-KEFS Tower Test performance in patients with lateral prefrontal cortex lesions: The importance of ...