| Left bundle branch block as a risk factor for progression to heart failure. | |
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MedLine Citation:
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PMID: 16890486 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The prevalence of conduction disturbances, particularly left bundle branch block (LBBB), is strongly correlated with age and with the presence of cardiovascular disease. LBBB has been reported to affect approximately 25% of the heart failure (HF) population and it is likely that the deleterious role of such conduction disorders in the progression to HF has been underestimated. The purpose of this article is to review the data from the literature indicating that LBBB may have a causative role, mediated through the resulting intra-ventricular asynchrony, in the deterioration of cardiac function and the development of cardiac remodelling and HF. It also aims to address the potential for future clinical therapies for this conduction disorder. |
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Authors:
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Faiez Zannad; Etienne Huvelle; Kenneth Dickstein; Dirk J van Veldhuisen; Christoph Stellbrink; Lars Køber; Serge Cazeau; Philippe Ritter; Aldo Pietro Maggioni; Roberto Ferrari; Philippe Lechat |
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Publication Detail:
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Type: Journal Article; Review Date: 2006-08-04 |
Journal Detail:
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Title: European journal of heart failure Volume: 9 ISSN: 1388-9842 ISO Abbreviation: Eur. J. Heart Fail. Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-01-16 Completed Date: 2007-08-06 Revised Date: 2011-06-08 |
Medline Journal Info:
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Nlm Unique ID: 100887595 Medline TA: Eur J Heart Fail Country: Netherlands |
Other Details:
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Languages: eng Pagination: 7-14 Citation Subset: IM |
Affiliation:
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CIC-INSERM-CHU de Nancy, Hôpital Jeanne d'Arc, Dommartin-lès-Toul, BP 303 - 54201 Toul Cedex, France. f.zannad@chu-nancy.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bundle-Branch Block
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complications,
physiopathology* Disease Progression Functional Laterality Heart Failure / etiology*, physiopathology Humans Risk Factors Ventricular Dysfunction, Left / physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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