Document Detail


Left bundle branch block: angiographic segmental wall motion abnormalities.
MedLine Citation:
PMID:  495497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ventricular wall motion as studied with contrast ventriculography has been judged normal in the few previously reported cases of patients with left bundle branch block who have neither coronary artery disease nor diffuse cardiomyopathy. However, recent echocardiographic studies have demonstrated a high frequency of segmental asynergy of the septal wall in such patients. In this study left ventricular wall motion was analyzed in 15 patients with left bundle branch block and without significant coronary artery disease or diffuse cardiomyopathy. Biplane cineangiograms from these patients were compared with those from 100 consecutive patients with normal intraventricular conduction and without coronary artery disease or cardiomyopathy using two techniques: qualitative visual inspection and a computer-assisted quantitative method. By qualitative review, 6 of 15 patients with left bundle branch block had regional akinesia or dyskinesia as compared with none of 100 patients with normal intraventricular conduction (chi square = 42.3; P less than 0.001). By quantitative review, 10 of 12 patients with left bundle branch block had abnormal wall motion along at least one hemiaxis. It is concluded that angiographic regional wall motion abnormalities are common in patients with left bundle branch block, even in the absence of coronary artery disease or diffuse cardiomyopathy. The abnormalities may result from the abnormal sequence of ventricular activation rather than from myocardial fibrosis.
Authors:
R S Williams; V S Behar; R H Peter
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  44     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1979 Nov 
Date Detail:
Created Date:  1979-12-20     Completed Date:  1979-12-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1046-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angiocardiography
Bundle-Branch Block / physiopathology*,  radiography
Cineangiography
Computers
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myocardial Contraction*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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