Document Detail

Left atrial or ventricular cannulation beyond 30 days for a Thoratec ventricular assist device.
MedLine Citation:
PMID:  8573858     Owner:  NLM     Status:  MEDLINE    
The authors used Thoratec left ventricular assist devices (VADs) for more than 30 days in eight patients. There were five left atrial (LA) (total, 513 days; range, 33-202 days) and three left ventricular (LV) cannulations (total, 484 days; range, 44-247 days). The flow provided by LA cannulation was less than that provided by LV cannulation. However, serial measurements of hematologic, renal, and hepatic function were similar for patients with LA and those with LV cannulation throughout support. Plasma free hemoglobin and lactate dehydrogenase (LDH) levels were similar for LA and LV patients. The five LA patients had one transient ischemic attack, one reversible ischemic neurologic deficit, and one stroke. The LV patients had no neurologic events (p = 0.20; LA versus LV total neurologic events). One LA patient and one LV patient died during support. Three LA patients underwent transplant, and one LA patient recovered native cardiac function. Two LV patients underwent transplant. In certain situations (e.g., recent anterior myocardial infarction; small left ventricular dimensions) LA cannulation may be advantageous. Neurologic events may be more common in LA patients, but in our small group this difference could be attributable to chance alone. LA or LV cannulation for a Thoratec VAD can provide adequate circulatory support for more than 30 days.
W L Holman; R C Bourge; C P Murrah; D C McGiffin; R D Spruell; E R Ferguson; J K Kirklin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  41     ISSN:  1058-2916     ISO Abbreviation:  ASAIO J.     Publication Date:    1995 Jul-Sep
Date Detail:
Created Date:  1996-03-12     Completed Date:  1996-03-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  M517-22     Citation Subset:  IM    
Division of Cardiothoracic Surgery, University of Alabama at Birmingham 35294-0007, USA.
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MeSH Terms
Cardiomyopathies / physiopathology,  therapy
Catheterization / adverse effects,  methods*
Embolism / etiology
Evaluation Studies as Topic
Heart Atria
Heart Ventricles
Heart-Assist Devices* / adverse effects
Hemoglobins / metabolism
Kidney / physiopathology
Liver / physiopathology
Myocardial Infarction / physiopathology,  therapy
Nervous System Diseases / etiology
Platelet Count
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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